PEBP (RKIP) Antibody

Our rabbit polyclonal PEBP (RKIP) antibody is formulated as neat serum. It is optimized in WB.

Catalog #: 1600-PEBP Categories: , Datasheet:

$109.00$325.00

  • SizePrice
Clear
Formulation:
Neat serum
Species Tested:
Rat
Applications:
WB 1:1000 Don't see your application?
Host Species:
Rabbit Polyclonal
Gene Name:
PEBP1
Molecular Weight:
~22 kDa
Cite This Antibody:
PhosphoSolutions Cat# 1600-PEBP, RRID:AB_2492204
Antigen/Purification: ExpandCollapse

The antigen is a native PEBP protein purified from rat.

The antibody is neat serum.

Biological Significance: ExpandCollapse

Phosphatidylethanolamine binding protein (PEBP), also known as Raf kinase inhibitory protein (RKIP) is a highly conserved multifunctional protein that modulates the Raf/MAPK signaling cascade and has been implicated as a suppressor of metastatic cancer (Trakul N et al., 2005). PEBP has been shown to not only inhibit cell proliferation but also to induce differentiation of human keratinocytes (Yamazaki et al., 2004). Dysregulation of calpain activity results in cellular degeneration in conditions such as Alzheimer’s disease and recently PEBP has been identified as a potential in vivo calpain substrate (Chen at al., 2006).

Synonyms: ExpandCollapse

• Epididymis luminal protein 210 antibody
• Epididymis secretory protein Li 34 antibody
• Epididymis secretory protein Li 96 antibody
• HCNP antibody
• HCNPpp antibody
• HEL 210 antibody
• HEL S 34 antibody
• HEL S 96 antibody
• Hippocampal cholinergic neurostimulating peptide antibody
• Neuropolypeptide h3 antibody
• PBP antibody
• PEBP antibody
• PEBP 1 antibody
• PEBP-1 antibody
• Pebp1 antibody
• PEBP1_HUMAN antibody
• Phosphatidylethanolamine binding protein antibody
• Phosphatidylethanolamine binding protein 1 antibody
• Prostatic binding protein antibody
• Prostatic-binding protein antibody
• R kip antibody
• Raf kinase inhibitor protein antibody
• Raf kinase inhibitory protein antibody
• RKIP antibody

Storage

100 µl neat serum. Adequate amount of material to conduct 10-mini Western Blots.

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Product Specific Protocols

Western Blotting

Click here to view our protocols page for Western blotting and lysate preparation.

General References

Trakul, N., Menard, R.E., Schade, G.R., Qian, Z. and Rosner, M.R., 2005. Raf kinase inhibitory protein regulates Raf-1 but not B-Raf kinase activation. Journal of Biological Chemistry, 280(26), pp.24931-24940. PMID: 15886202

Yamazaki, T., Nakano, H., Hayakari, M., Tanaka, M., Mayama, J. and Tsuchida, S., 2004. Differentiation induction of human keratinocytes by phosphatidylethanolamine-binding protein. Journal of Biological Chemistry, 279(31), pp.32191-32195. PMID: 15155742

Chen, Q., Wang, S., Thompson, S.N., Hall, E.D. and Guttmann, R.P., 2006. Identification and characterization of PEBP as a calpain substrate. Journal of Neurochemistry, 99(4), pp.1133-1141. PMID: 17018026

  • 5 – Excellent (publishable, performed ideally)
  • 4 – Good (publishable, would use again)
  • 3 – Average (publishable, might use again)
  • 2 – Poor (unpublishable, signal inconclusive)
  • 1 – No signal (unpublishable)
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