Anti-Adiponectin (C-terminal region) Antibody (M576)

Name: Anti-Adiponectin (C-terminal region) Antibody
Brand: PhosphoSolutions
SKU: AM5761
Price: 309.0 USD
Availability: InStock

from PhosphoSolutions

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

M576

Applications

Host Species

Mouse

Format

Protein G Purified

Gene Name

ADIPOQ

Molecular Weight

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Western blot analysis of mouse white adipose tissue (lanes 1 & 3) and human recombinant full length adiponectin (lanes 2 & 4). The blot was probed with mouse monoclonals anti-Adiponectin (C-terminal) antibody M577 (lanes 1 & 2) or anti-Adiponectin (C-terminal) antibody M576 (lanes 3 & 4).

Volume: 100 µL

Variant

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$309

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Product Details

Target

Adiponectin (C-terminal region)

Target Description

Adiponectin is an adipokine that is secreted primarily from adipocytes and functions in glucose regulation and lipid metabolism. It has also been shown to play a major role in energy homeostasis. Studies report adiponectin secretion in bone, mammary glands, salivary glands, and cardiac tissue in limited quantities. It forms a homo-oligomeric structure and is homologous to complement factor C1q, collagen type VIII, and collagen type X. In humans and mice with low adiponectin levels, increased obesity and insulin resistance is observed. Adiponectin, typically an anti-inflammatory agent, has been shown to exert pro-inflammatory effects in nonmetabolic disease such as irritable bowel syndrome. Low levels of adiponectin in blood have been correlated with higher incidence and poorer prognosis in several cancers, including breast cancer.

Format

Protein G Purified

Clonality

Monoclonal

Clone

M576

Isotype

IgG1

Applications

Host Species

Mouse

Gene Name

ADIPOQ

Molecular Weight

Antigen

Clone (M576) was generated from a recombinant protein that included amino acid residues within the C-terminal region of mouse Adiponectin. This sequence has high homology with similar regions in rat and human adiponectin.

Species Reactivity

Human, Mouse, Rat

Storage

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Physical State

Liquid

Buffer

PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol

Dilution Ranges

WB: 1:500

Conjugate

Unconjugated

Specificity

This antibody detects a 30 kDa* protein on SDS-PAGE immunoblots of human and mouse serum, as well as detects full length human and mouse recombinant proteins.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

ACDC, ACRP30, APM1, GBP28

UniProt Details

UniProt (Human): Q15848
UniProt (Immunogen Species): Q60994

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Anti-Adiponectin (C-terminal region) Antibody (M576)

Anti-Adiponectin (C-terminal region) Antibody
SKU: AM5761

Bulk Order Anti-Adiponectin (C-terminal region) Antibody

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Anti-Adiponectin (C-terminal region) Antibody (M576)

Anti-Adiponectin (C-terminal region) Antibody SKU: AM5761

Bulk Order Anti-Adiponectin (C-terminal region) Antibody

Product Details

Anti-Adiponectin (C-terminal region) Antibody
SKU: AM5761