Anti-VGlut1 Antibody (N28/9)

Name: Anti-VGlut1 Antibody
Brand: NeuroMab
SKU: 75-066
Price: 335.0 USD
Availability: InStock

from NeuroMab Datasheet Trial Size

filler

Clonality

Monoclonal

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Slc17a7 Bnpi Vglut1

Molecular Weight

52 kDa

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Immunoblot against extracts of COS cells transfected with untagged VGlut or Kv2.1 plasmid and probed with N28/9 (left) or N52A/42 (right) TC supe.

Adult rat hippocampal immunohistochemistry.

Adult rat whole brain immunohistochemistry.

Immunoblot against extracts of COS cells transfected with untagged VGlut or Kv2.1 plasmid and probed with N28/9 (left) or N52A/42 (right) TC supe.

Volume: 100 µL

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Price:

$335

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Product Details

Target

VGlut1

Target Description

Vesicular glutamate transporter 1 (Vglut1) is encoded by the gene Slc17a7 and belongs to the vesicular glutamate transporter family. Vglut1 is expressed in glutamatergic neurons in brain regions including the cerebellum, cerebral cortex and hippocampus at synaptic vesicles. Isoform 2 is expressed in retinal. Vglut1 functions to uptake glutamate into synaptic vesicles in excitatory neural cells. Altered expression of Vglut1 has been implicated in several neurological and psychiatric diseases including Alzheimer’s disease, Parkinson’s disease, epilepsy and schizophrenia.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N28/9

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Slc17a7 Bnpi Vglut1

Molecular Weight

52 kDa

Antigen

Fusion protein amino acids 493-560 (cytoplasmic C-terminus) of rat VGlut1 (also known as Vesicular glutamate transporter 1, Brain-specific Na(+)-dependent inorganic phosphate cotransporter, Bnpi, Solute carrier family 17 member 7 and Slc17a7, accession number Q62634); Mouse: 97% identity (66/68 amino acids identical); Human: 95% identity (65/68 amino acids identical); 50% identity with VGlut2 or VGlut3

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2187693

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with VGlut2 or VGlut3

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Vesicular glutamate transporter 1 (VGluT1) (Brain-specific Na(+)-dependent inorganic phosphate cotransporter) (Solute carrier family 17 member 7)

UniProt Details

UniProt (Human): Q9P2U7
UniProt (Immunogen Species): Q62634

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Anti-VGlut1 Antibody (N28/9)

Anti-VGlut1 Antibody
SKU: 75-066

Product Details

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Anti-VGlut1 Antibody (N28/9)

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Anti-VGlut1 Antibody
SKU: 75-066