Anti-TRAIL R3 Antibody

Name: Anti-TRAIL R3 Antibody
Brand: PhosphoSolutions
SKU: 24297
Price: 430.0 USD
Availability: InStock

Our TRAIL R3 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human TRAIL R3 and is antigen affinity purified. It is great for use in WB.

Species Reactivity

Human

Applications

Host Species

Rabbit

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SKU: 24297

Product Details

Target

TRAIL R3

Target Description

DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

Host Species

Rabbit

Gene Name

TNFRSF10C

Antigen

Synthetic peptide corresponding to amino acids from the N-terminal region of human TRAIL R3 protein

Species Reactivity

Human

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with the N terminus of the mature human TRAIL-R3 protein

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

TNFRSF10C, DCR1, LIT, TRAILR3, TRID, UNQ321/PRO366

UniProt Details

UniProt (Human): O14798
UniProt (Immunogen Species): O14798

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Anti-TRAIL R3 Antibody

SKU: 24297

Product Details

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