Anti-TRAIL R2 (DR5) Antibody

Name: Anti-TRAIL R2 (DR5) Antibody
Brand: PhosphoSolutions
SKU: 24296
Price: 430.0 USD
Availability: InStock

Our TRAIL R2 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human TRAIL R2 and is antigen affinity purified. It is great for use in WB.

Western Blot of HeLa cell lysate showing specific immunolabeling of TRAIL-R2.

Species Reactivity

Human

Applications

Host Species

Rabbit

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SKU: 24296

Product Details

Target

TRAIL R2

Target Description

TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A distinct receptor for TRAIL, TRAIL-R2 (aka Death Receptor 5 (DR5)), by ligand-based affinity purification and subsequent molecular cloning. TRAIL-R2 is widely expressed and the gene encoding TRAIL-R2 is located on human chromosome 8p22-21. TRAIL-R2 engages a caspase-dependent apoptotic pathway but, in contrast to TRAIL-R1, TRAIL-R2 mediates apoptosis via the intracellular adaptor molecule FADD/MORT1.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

Host Species

Rabbit

Gene Name

TNFRSF10B

Antigen

Synthetic peptide corresponding to amino acids from the N-terminal region of human TRAIL R2 protein

Species Reactivity

Human

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with the N terminus of the human TRAIL-R2 protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9, UNQ160/PRO186

UniProt Details

UniProt (Human): O14763
UniProt (Immunogen Species): O14763

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Anti-TRAIL R2 (DR5) Antibody

SKU: 24296

Product Details

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