Anti-Slingshot-1L (C-terminal region) Antibody
Primary Antibody
Human, Mouse, Rat
ICC, IHC, WB
Rabbit
Antigen Affinity Purified
SSH1
150
Western blot of human recombinant SSH1L untreated (lanes 1 & 3) or treated with lambda phosphatase (lanes 2 & 4) and rat PC12 cells unstimulated (lanes 5 & 7) or stimulated with calyculin A (lanes 6 & 8). The blots were probed with anti-SSH1L (C-term.) (lanes 1, 2, 5, & 6) or anti-SSH1L (Ser-978) (lanes 3, 4, 7, & 8).
Product Specific References for Applications and Species
- Immunocytochemistry: Human | Mouse
- Immunohistochemistry: Human | Mouse
- Western Blot: Human | Mouse | Rat
| Immunocytochemistry: Human | ||
| PMID | Dilution | Publication |
| 25698445 | not listed | Woo, JA, et al. 2015. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell death and differentiation, 921-934. |
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 37463212 | not listed | Cazzaro, S, et al. 2023. Slingshot Homolog-1-mediated Nrf2 Sequestration Tips the Balance from Neuroprotection to Neurodegeneration in Alzheimer's Disease. PNAS: USA, e2217128120. |
| 36637427 | 1:100 | Cazzaro,S, et al. 2023. Slingshot homolog-1 amplifies mitochondrial abnormalities by distinctly impairing health and clearance of mitochondria. Human molecular genetics, 1660-1672. |
| 34342389 | not listed | Lee, KY, et al. 2021. Infantile spasms-linked Nedd4-2 mediates hippocampal plasticity and learning via cofilin signaling. EMBO reports, e52645. |
| 33044112 | not listed | Fang, C, et al. 2021. SSH1 impedes SQSTM1/p62 flux and MAPT/Tau clearance independent of CFL (cofilin) activation. Autophagy, 2144-2165. |
| 31577955 | not listed | Zhang, Z, et al. 2019. The Schizophrenia Susceptibility Gene OPCML Regulates Spine Maturation and Cognitive Behaviors through Eph-Cofilin Signaling. Cell reports, 49-61. |
| 25698445 | not listed | Woo, JA, et al. 2015. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell death and differentiation, 921-934. |
| Immunohistochemistry: Human | ||
| PMID | Dilution | Publication |
| 34284854 | not listed | Li, M, et al. 2021. Phosphorylation of Cofilin-1 Enhances Paclitaxel Resistance of Epithelial Ovarian Cancer Cells by Inhibiting Apoptosis. Biomedical and environmental sciences : BES, 465-477. |
| 25698445 | not listed | Woo, JA, et al. 2015. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell death and differentiation, 921-934. |
| 25684665 | 1:100 | Wang, Y, et al. 2015. Cofilin-phosphatase slingshot-1L (SSH1L) is over-expressed in pancreatic cancer (PC) and contributes to tumor cell migration. Cancer Letters, 171-176. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 36637427 | 1:100 | Cazzaro,S, et al. 2023. Slingshot homolog-1 amplifies mitochondrial abnormalities by distinctly impairing health and clearance of mitochondria. Human molecular genetics, 1660-1672. |
| 25698445 | not listed | Woo, JA, et al. 2015. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell death and differentiation, 921-934. |
| Western Blot: Human | ||
| PMID | Dilution | Publication |
| 25698445 | not listed | Woo, JA, et al. 2015. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell death and differentiation, 921-934. |
| 19339277 | not listed | Kim, JS, et al. 2009. Reactive oxygen species regulate a slingshot-cofilin activation pathway. Moleculare biology of the cell, 2650-2660. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 37463212 | not listed | Cazzaro, S, et al. 2023. Slingshot Homolog-1-mediated Nrf2 Sequestration Tips the Balance from Neuroprotection to Neurodegeneration in Alzheimer's Disease. PNAS: USA, e2217128120. |
| 36637427 | 1:1000 | Cazzaro,S, et al. 2023. Slingshot homolog-1 amplifies mitochondrial abnormalities by distinctly impairing health and clearance of mitochondria. Human molecular genetics, 1660-1672. |
| 34342389 | not listed | Lee, KY, et al. 2021. Infantile spasms-linked Nedd4-2 mediates hippocampal plasticity and learning via cofilin signaling. EMBO reports, e52645. |
| 33044112 | not listed | Fang, C, et al. 2021. SSH1 impedes SQSTM1/p62 flux and MAPT/Tau clearance independent of CFL (cofilin) activation. Autophagy, 2144-2165. |
| 31577955 | not listed | Zhang, Z, et al. 2019. The Schizophrenia Susceptibility Gene OPCML Regulates Spine Maturation and Cognitive Behaviors through Eph-Cofilin Signaling. Cell reports, 49-61. |
| 31400829 | 1:500 | Tedeschi, A, et al. 2019. ADF/Cofilin-Mediated Actin Turnover Promotes Axon Regeneration in the Adult CNS. Neuron, 1073-1085. |
| 24464040 | 1:1000 | Parisiadou, L, et al. 2014. LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity. Nature neuroscience, 367-376. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 37138671 | 1:1000 | Ramos-Alvarez, I, et al. 2023. Cofilin Activation in Pancreatic Acinar Cells Plays a Pivotal Convergent Role for Mediating CCK-stimulated Enzyme Secretion and Growth. Frontiers in Physiology, 1147572. |
| 28923249 | 1:500 | Caso, S, et al. 2017. AKAP-Lbc mediates protection against doxorubicin-induced cardiomyocyte toxicity. Biochimica et biophysica acta. Molecular cell research, 2336-2346. |
| 27073215 | 1:375 | Lauterborn, J, et al. 2017. Cofilin Activation Is Temporally Associated with the Cessation of Growth in the Developing Hippocampus. Cerebral cortex (New York, N.Y. : 1991), 2640-2651. |
| 24962708 | 1:800 | Li, Y, et al. 2014. LIMK-dependent actin polymerization in primary sensory neurons promotes the development of inflammatory heat hyperalgesia in rats. Science signaling, ra61. |