Anti-SHP1 (Tyr-536), Phosphospecific Antibody

Our SHP1 (Tyr-536) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat SHP1 (Tyr-536) and is antigen affinity purified. It is great for use in WB.



SKU: SP1571

Volume: 100 µL
Price:
Sale price$329

Product Specific References for Applications and Species

Flow Cytometry: Human
PMID Dilution Publication
24405902not listedLe Page, A, et al. 2014. Downregulation of inhibitory SRC homology 2 domain-containing phosphatase-1 (SHP-1) leads to recovery of T cell responses in elderly. Cell communication and signaling, 2.
Immunocytochemistry: Human
PMID Dilution Publication
29307735not listedLe Page, A, et al. 2018. Signal transduction changes in CD4+ and CD8+ T cell subpopulations with aging. Experimental Gerontology, 128-139.
Immunocytochemistry: Mouse
PMID Dilution Publication
25876760not listedCerny, O, et al. 2015. Bordetella pertussis Adenylate Cyclase Toxin Blocks Induction of Bactericidal Nitric Oxide in Macrophages through cAMP-Dependent Activation of the SHP-1 Phosphatase. Journal of immunology (Baltimore, Md. : 1950), 4901-4913.
Reverse-Phase Protein Assay: Human
PMID Dilution Publication
29187853not listedPresotto, D, et al. 2017. Fine-Tuning of Optimal TCR Signaling in Tumor-Redirected CD8 T Cells by Distinct TCR Affinity-Mediated Mechanisms. Frontiers in immunology, 1564.
Western Blot: Human
PMID Dilution Publication
24405902not listedLe Page, A, et al. 2014. Downregulation of inhibitory SRC homology 2 domain-containing phosphatase-1 (SHP-1) leads to recovery of T cell responses in elderly. Cell communication and signaling, 2.
24713856not listedKataoka, TR, et al. 2013. CD72 regulates the growth of KIT-mutated leukemia cell line Kasumi-1. Scientific reports, 2861.
23391724not listedHebeisen, M, et al. 2013. SHP-1 phosphatase activity counteracts increased T cell receptor affinity. The Journal of Clinical Investigation, 1044-1056.
Western Blot: Mouse
PMID Dilution Publication
288114761:1000Mkaddem, SB, et al. 2017. Lyn and Fyn function as molecular switches that control immunoreceptors to direct homeostasis or inflammation. Nature communications, 246.
28250424not listedChoi, S, et al. 2017. THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1. Nature immunology, 433-441.
27271569not listedMoogk, D, et al. 2016. Constitutive Lck Activity Drives Sensitivity Differences between CD8+ Memory T Cell Subsets. Journal of immunology (Baltimore, Md. : 1950), 644-654.
25239131not listedKataoka, TR, et al. 2015. CD72 negatively regulates mouse mast cell functions and down-regulates the expression of KIT and FcεRIα. International immunology, 95-103.
24990897not listedZhou, X, et al. 2014. Leishmania infantum-chagasi activates SHP-1 and reduces NFAT5/TonEBP activity in the mouse kidney inner medulla. American Journal of Physiology. Renal Physiology, F516-524.
19201855not listedVerhagen, AM, et al. 2009. A kinase-dead allele of Lyn attenuates autoimmune disease normally associated with Lyn deficiency. Journal of immunology (Baltimore, Md. : 1950), 2020-2029.
Western Blot: Rat
PMID Dilution Publication
28017654not listedPark, SY, et al. 2017. Hippocalcin Promotes Neuronal Differentiation and Inhibits Astrocytic Differentiation in Neural Stem Cells. Stem Cell Reports, 95-111.
26342897not listedChoi, YR, et al. 2015. FcγRIIB mediates the inhibitory effect of aggregated α-synuclein on microglial phagocytosis. Neurobiology of Disease, 90-99.
24140598not listedTibaldi, E, et al. 2014. The tyrosine phosphatase SHP-1 inhibits proliferation of activated hepatic stellate cells by impairing PDGF receptor signaling. Biochimica et Biophysica acta, 288-298.

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