Anti-Ribosomal S6 Kinase 2 Antibody

Name: Anti-Ribosomal S6 Kinase 2 Antibody
Brand: PhosphoSolutions
SKU: 1850-RSK2
Price: 415.0 USD
Availability: InStock

from PhosphoSolutions Datasheet Trial Size Pooled Serum

1 Citation

Our Anti-Ribosomal S6 kinase 2 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human Ribosomal S6 kinase 2 and is antigen affinity purified from pooled serum. It is great for use in WB.

Product Type

Primary Antibody

Species Reactivity

Human

Expected Reactivity

Bovine, Canine, Chicken, Mouse, Rat

Applications

Host Species

Rabbit

Format

Antigen Affinity Purified from Pooled Serum

Gene Name

RPS6KA2

Molecular Weight

90 kDa

Go to Full Product Details

Western blot of HeLa cell lysate showing specific immunolabeling of the ~90 kDa RSK2 protein.

Volume: 100 µL

Variant

Price:

$415

Quantity:

Bulk Order Anti-Ribosomal S6 Kinase 2 Antibody

Product Details

Target

Ribosomal S6 kinase 2

Target Description

The p90 ribosomal S6 kinases (RSK)1–4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin–Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006).

Format

Antigen Affinity Purified from Pooled Serum

Clonality

Polyclonal

Isotype

IgG

Applications

Host Species

Rabbit

Gene Name

RPS6KA2

Molecular Weight

90 kDa

Antigen

Synthetic peptide corresponding to amino acid residues from the C-terminal region on mouse ribosomal S6 kinase 2, conjugated to keyhole limpet hemocyanin (KLH).

Species Reactivity

Human

Expected Reactivity

Bovine, Canine, Chicken, Mouse, Rat

Antibody Registry ID

AB_2492233

Storage

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Physical State

Liquid

Production Notes

Prepared from pooled rabbit serum by affinity purification using a column to which C-terminal peptide immunogen was coupled.

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Dilution Ranges

WB: 1:1000

Conjugate

Unconjugated

Specificity

Specific for endogenous levels of the ~90 kDa RSK2 protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

90 kDa ribosomal protein S6 kinase 2 antibody, HU 2 antibody, KS6A2_HUMAN antibody, MAP kinase activated protein kinase 1c antibody, MAP kinase-activated protein kinase 1c antibody, MAPK-activated protein kinase 1c antibody, MAPKAP kinase 1c antibody, MAPKAPK-1c antibody, MAPKAPK1C antibody, Mitogen.activated protein kinase-activated protein kinase 1C antibody, p90 RSK3 antibody, p90-RSK 2 antibody, p90RSK2 antibody, pp90RSK3 antibody, Ribosomal protein S6 kinase alpha-2 antibody, ribosomal protein S6 kinase 90kDa polypeptide 2 antibody, Ribosomal S6 kinase 3 antibody, RPS6KA2 antibody, RSK3 antibody, RSK 3 antibody, RSK antibody, RSK-3 antibody, S6K alpha antibody, S6K alpha 2 antibody, S6K-alpha-2 antibody

UniProt Details

UniProt (Human): Q15349
UniProt (Immunogen Species): Q9WUT3

NCBI Gene ID

20112

Product Specific References for Applications and Species

Western Blot: Mouse

Western Blot: Mouse
PMID	Dilution	Publication
27339393	not listed	Hegde, S., et al. 2016. Phosphodiesterase 11A (PDE11A), enriched in ventral hippocampus neurons, is required for consolidation of social but not nonsocial memories in mice. Neuropsychopharmacology, 41(12), p. 2920-2931.

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Anti-Ribosomal S6 Kinase 2 Antibody

Our Anti-Ribosomal S6 kinase 2 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human Ribosomal S6 kinase 2 and is antigen affinity purified from pooled serum. It is great for use in WB.