Our Anti-Prosurfactant Protein C primary antibody from PhosphoSolutions is rabbit polyclonal. It detects human and mouse Prosurfactant Protein C and is antigen affinity purified. It is great for use in IHC.
Immunofluorescence of mouse lung showing specific labeling of alveolar type 2 epithelial cells using anti-Prosurfactant Protein C antibody in red. Nuclei are stained blue.
Pulmonary surfactant Protein C (SP-C) is one of 4 distinct surfactant proteins; SP-A, SP-B, SP-C and SP-D. SP-C is produced by proteolytic cleavage of a larger precursor known as Prosurfactant Protein C which is expressed exclusively in the lungs and widely used as a marker for alveolar type 2 epithelial cells. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency and are associated with interstitial lung disease in older infants, children, and adults.
Antigen Affinity Purified
Synthetic peptide from the N-terminal region of mouse Prosurfactant Protein C.
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Prepared from rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.
Specific for endogenous levels of the ~21 kDa Prosurfactant Protein C.
Immunohistochemistry performed on each lot.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
United States of America
After date of receipt, stable for at least 1 year at -20°C.
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