Name: Anti-Olig1 Antibody
Brand: PhosphoSolutions
SKU: 1537-Olig1
Price: 415.0 USD
Availability: InStock

Our Anti-Olig1 primary antibody from PhosphoSolutions is rabbit polyclonal. It detects human, mouse, and rat Olig1 and is protein a purified. It is great for use in WB, IHC, ICC, IP.

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC, IP, WB

Host Species

Rabbit

Format

Protein A purified

Gene Name

OLIG1

Molecular Weight

27 kDa

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Immunostaining of primary rat oligodendrocytes using anti-Olig1 (cat. 1537-OLIG1, red, 1:100).

Western blot of neonatal rat brain lysate showing specific immunolabeling of the ~ 27 kDa Olig1 protein.

Volume: 100 µL

Variant

Price:

$415

Quantity:

Bulk Order Anti-Olig1 Antibody

Product Details

Target

Olig1

Target Description

Olig genes have been identified as the earliest known markers of oligodendrocyte lineage determination to date (Zhou et al., 2000). Olig1 is a transcription factor which promotes formation and maturation of oligodendrocytes, especially within the brain. It is expressed in the ventral spinal cord as early as 9.5 dpc and by 15.5 dpc, olig1 is dispersed throughout the gray matter. In the postnatal brain, it is present preferentially in the white matter, such as corpus callosum and cerebellar medulla. Olig1 has been demonstrated as necessary in the repair of brain lesions in patients with multiple sclerosis (Arnett et al. 2004).

Format

Protein A purified

Clonality

Polyclonal

Isotype

IgG

Applications

ICC, IHC, IP, WB

Host Species

Rabbit

Gene Name

OLIG1

Molecular Weight

27 kDa

Antigen

Recombinant mouse Olig1.

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2492192

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Production Notes

Protein A purified rabbit serum

Buffer

100 mM Glycine, 200 mM Tris, pH 8.0

Dilution Ranges

WB: 1:3000
WB Brain: 1:3000
IHC: 1:100
ICC: 1:100
IP: 1:50

Conjugate

Unconjugated

Specificity

Specific for endogenous levels of the ~27 kDa Olig1 protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

Basic domain helix loop helix protein class B 6 antibody, Basic domain helix loop helix protein class B6 antibody, BHLH B6 antibody, BHLHB 6 antibody, bHLHb6 antibody, bHLHe21 antibody, Class B basic helix-loop-helix protein 6 antibody, Class E basic helix-loop-helix protein 21 antibody, Olig 1 antibody, Olig1 antibody, OLIG1_HUMAN antibody, Oligo 1 antibody, Oligo1 antibody, Oligodendrocyte lineage transcription factor 1 antibody, Oligodendrocyte specific bHLH transcription factor 1 antibody, Oligodendrocyte transcription factor 1 antibody

UniProt Details

UniProt (Human): Q8TAK6
UniProt (Immunogen Species): Q9JKN5

NCBI Gene ID

50914

Product Specific References for Applications and Species

Chromatin Immunoprecipitation: Mouse

Chromatin Immunoprecipitation: Mouse
PMID	Dilution	Publication
31130512	not listed	Xu, R., et al. 2019. OLIG2 drives abnormal neurodevelopmental phenotypes in human iPSC-based organoid and chimeric mouse models of down syndrome. Cell Stem Cell, 24(6), pp.908-926.

Product Specific Protocols

Olig1 ICC Protocol: Download

Western Blot Protocol: Download

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Anti-Olig1 Antibody

Our Anti-Olig1 primary antibody from PhosphoSolutions is rabbit polyclonal. It detects human, mouse, and rat Olig1 and is protein a purified. It is great for use in WB, IHC, ICC, IP.