Name: Anti-GABA Transporter (GAT) 2 Antibody
Brand: PhosphoSolutions
SKU: 881-GAT2
Price: 415.0 USD
Availability: InStock

Our Anti-GABA Transporter (GAT) 2 primary antibody from PhosphoSolutions is rabbit polyclonal. It detects mouse and rat GABA Transporter (GAT) 2 and is affinity purified. It is great for use in WB, IHC.

Product Type

Primary Antibody

Species Reactivity

Rat

Applications

IHC, WB

Host Species

Rabbit

Format

Affinity Purified

Gene Name

SLC6A13

Molecular Weight

67 kDa

Go to Full Product Details

Western blot of mouse whole brain lysate showing specific immunolabeling of the ~67 kDa GAT-2 protein.

Volume: 100 µL

Variant

Price:

$415

Quantity:

Bulk Order Anti-GABA Transporter (GAT) 2 Antibody

Product Details

Target

GABA Transporter (GAT) 2

Target Description

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABA-A receptor (GABA-A-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex (Conti et al., 1999)

Format

Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

IHC, WB

Host Species

Rabbit

Gene Name

SLC6A13

Molecular Weight

67 kDa

Antigen

Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat GAT2, conjugated to keyhole limpet hemocyanin (KLH).

Species Reactivity

Rat

Antibody Registry ID

AB_2492120

Storage

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Physical State

Liquid

Production Notes

Prepared from rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Dilution Ranges

WB: 1:100-200
WB Brain: 1:100-200
IHC: 1:100-200

Conjugate

Unconjugated

Specificity

Specific for endogenous levels of the ~82 kDa GAT-2 protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

GABA transport protein antibody, GAT 2 antibody, GAT-2 antibody, GAT2 antibody, GAT3 antibody, S6A13_HUMAN antibody, SLC6A13 antibody, Sodium- and chloride-dependent GABA transporter 2 antibody, Solute carrier family 6 (Neurotransmitter transporter GABA), member 13 antibody, Solute carrier family 6 member 13 antibody

UniProt Details

UniProt (Immunogen Species): P31646

NCBI Gene ID

171163

Product Specific References for Applications and Species

Immunohistochemistry: Rat

Immunohistochemistry: Rat
PMID	Dilution	Publication
8915826	not listed	Johnson, J., et al. 1997. Multiple γ-aminobutyric acid plasma membrane transporters (GAT-1, GAT-2, GAT-3) in the rat retina. The Journal of Comparative Neurology, 375(2), 212.

Product Specific Protocols

Western Blot Protocol: Download

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Anti-GABA Transporter (GAT) 2 Antibody

Our Anti-GABA Transporter (GAT) 2 primary antibody from PhosphoSolutions is rabbit polyclonal. It detects mouse and rat GABA Transporter (GAT) 2 and is affinity purified. It is great for use in WB, IHC.