Anti-CLAC-P (NC3 region) Antibody

Name: Anti-CLAC-P (NC3 region) Antibody
Brand: PhosphoSolutions
SKU: 24308
Price: 415.0 USD
Availability: InStock

from PhosphoSolutions

Our CLAC-P (NC3 region) rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human and mouse CLAC-P (NC3 region) and is antigen affinity purified. It is great for use in WB.

Product Type

Primary Antibody

Species Reactivity

Human, Mouse

Applications

Host Species

Rabbit

Format

Antigen Affinity Purified

Gene Name

COL25A1

Go to Full Product Details

Western Blot of Lane 1: full-length CLAC-P (lysate), Lane 2: secreted form of CLAC-P (media), Lane 3: COLXIII (lysate), Lane 4 degrees COLXIII (media), Lane 5: COLXXIII (lysate), Lane 6: COLXXIII (media) showing specific immunolabeling of Collagen XXV alpha 1.

Immunohistochemistry of the neocortex of Alzheimer's diseased brain sections (floating, fixed with 10% formalin for 24 hrs) showing specific staining of Collagen XXV.

Title: 100 µL

Variant

Price:

$415

Quantity:

Bulk Order Anti-CLAC-P (NC3 region) Antibody

Product Details

Target

CLAC-P (NC3 region)

Target Description

Antibodies against senile plaque (SP) amyloid obtained a clone 9D2, which labeled amyloid fibrils in SPs and reacted with approximately 50/100 kDa polypeptides in Alzheimer's disease (AD) brains. The 9D2 antigen was identified as CLAC (collagen-like Alzheimer amyloid plaque component), and its precursor as CLAC-P/collagen type XXV. Both secreted and membrane-tethered forms of CLAC-P/collagen type XXV specifically bound to fibrillized Abeta, implicating these proteins in beta-amyloidogenesis and neuronal degeneration in AD

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

Host Species

Rabbit

Gene Name

COL25A1

Antigen

Synthetic peptide corresponding to amino acids from the NC23 region of human CLAC-P

Species Reactivity

Human, Mouse

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with the NC3 region of human and mouse CLAC-P.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

COL25A1, Collagen alpha-1 XXV chain, Alzheimer disease amyloid-associated protein, AMY, Collagen-like Alzheimer amyloid plaque component

UniProt Details

UniProt (Human): Q9BXS0
UniProt (Immunogen Species): Q9BXS0

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Anti-CLAC-P (NC3 region) Antibody

Our CLAC-P (NC3 region) rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human and mouse CLAC-P (NC3 region) and is antigen affinity purified. It is great for use in WB.