Axin, an important regulator of beta-catenin, is frequently mutated in human hepatocellular carcinomas (HCCs), and transduction of the wild-type Axin gene (AXIN1) induces apoptosis in HCC cells as well as in colon cancer cells. A novel gene, AXUD1 (AXIN1 up-regulated), has enhanced expression in response to exogenously expressed AXIN1. It is expressed in all human tissues examined, most abundantly in lung, placenta, skeletal muscle, pancreas and leukocytes. Data suggests that AXUD1 may have a tumor-suppressor function in those organs.
Antigen Affinity Purified
Synthetic peptides corresponding to amino acids from the N-terminal and C-terminal regions of human AXUD1 protein
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
PBS + 0.02% NaN3
WB Brain: 1:500-1:1000
Reacts with the N-terminal and C-terminal regions of human AXUD1 protein
Western blots performed on each lot.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
After date of receipt, stable for at least 1 year at -20°C.
Cysteine/serine-rich nuclear protein 1, CSRNP1, Axin-1 up-regulated gene 1 protein, Protein URAX1, TGF-beta-induced apoptosis protein 3, TAIP-3