Our Adiponectin (C-terminal region) mouse monoclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat Adiponectin (C-terminal region) and is Protein G purified. It is great for use in WB.
Western blot analysis of mouse white adipose tissue (lanes 1 & 3) and human recombinant full length adiponectin (lanes 2 & 4). The blot was probed with mouse monoclonals anti-Adiponectin (C-terminal) antibody M577 (lanes 1 & 2) or anti-Adiponectin (C-terminal) antibody M576 (lanes 3 & 4).
Adiponectin is an adipokine that is secreted primarily from adipocytes and functions in glucose regulation and lipid metabolism. It has also been shown to play a major role in energy homeostasis. Studies report adiponectin secretion in bone, mammary glands, salivary glands, and cardiac tissue in limited quantities. It forms a homo-oligomeric structure and is homologous to complement factor C1q, collagen type VIII, and collagen type X. In humans and mice with low adiponectin levels, increased obesity and insulin resistance is observed. Adiponectin, typically an anti-inflammatory agent, has been shown to exert pro-inflammatory effects in nonmetabolic disease such as irritable bowel syndrome. Low levels of adiponectin in blood have been correlated with higher incidence and poorer prognosis in several cancers, including breast cancer.
Protein G Purified
Clone (M577) was generated from a recombinant protein that included amino acid residues within the C-terminal region of mouse adiponectin. This sequence has high homology with similar regions in rat and human adiponectin.
Human, Mouse, Rat
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol
This antibody detects a 30 kDa* protein on SDS-PAGE immunoblots of human and mouse serum, as well as detects full length human and mouse recombinant proteins.
Western blots performed on each lot.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
After date of receipt, stable for at least 1 year at -20°C.