Visinin-Like Protein 1 (VSNL1) Antibody

Catalog #: 2145-VSNL1 Categories: , , Datasheet:

$109.00$365.00

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Neuronal marker that works great in IHC!

 

Formulation:
Protein G Purified
Species Tested:
Human, Mouse, Rat
Applications:
WB 1:2000IHC 1:500-1:1000ICC 1:500-1:1000
Species:
Mouse Monoclonal
Gene Name:
VSNL1
Molecular Reference:
~ 22 kDa
Cite This Antibody:
PhosphoSolutions Cat# 2145-VSNL1, RRID:AB_2492285
Antigen/Purification: ExpandCollapse

The antigen is recombinant full length human VSNL1 expressed in and purified from E. Coli.

The antibody is Protein G purified culture supernatant.

Biological Significance: ExpandCollapse

Visinin-like protein 1 (VSNL1), also known as VILIP1, is a calcium sensor protein expressed exclusively in neurons. Highest levels of VSNL1 expression are found in cerebellar Purkinje cells. VSNL1 has been implicated in the modulation of cell signaling cascades via regulation of adenyl cyclase activity (Braunewell et al., 1997). Additionally, VSNL1 has been associated with amyloid plaques and neurofibrillar tangles in Alzheimer’s disease (Schnurra et al., 2001).

Synonyms: ExpandCollapse

• 21 kDa CABP antibody
• Hippocalcin like protein 3 antibody
• Hippocalcin-like protein 3 antibody
• HLP 3 antibody
• HLP3 antibody
• HPCAL 3 antibody
• HPCAL3 antibody
• HUVISL1 antibody
• Neural visinin-like protein 1 antibody
• Neural visinin-like type 1 protein antibody
• Neurocalcin alpha antibody
• NVL 1 antibody
• NVL1 antibody
• Nvp1 antibody
• OZ1 antibody
• Ratnvp1 antibody
• VILIP antibody
• VILIP1 antibody
• VILIP-1 antibody
• Visinin antibody
• Visinin like 1 antibody
• Visinin like protein 1 antibody
• Visinin-like protein 1 antibody
• VISL 1 antibody
• VISL1 antibody
• VISL1_HUMAN antibody
• VLP-1 antibody
• Vnsl1 antibody
• Vsnl1 antibody

Storage

100 µl liquid containing 10 mM sodium azide. Adequate amount of material to conduct 10-mini Western Blots.

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Product Specific Protocols

Immunohistochemistry

Rat cerebellum (free floating section)
Rat cerebellum

Western Blotting

Click here to view our protocols page for Western blotting and lysate preparation.

General References

Braunewell KH, Spilker C, Behnisch T, Gundelfinger ED (1997) The neuronal calcium-sensor protein VILIP modulates cyclic AMP accumulation in stably transfected C6 glioma cells: amino-terminal myristoylation determines functional activity. J. Neurochem. 68 (5): 2129–39. PMID: 9109541

Schnurra I, Bernstein HG, Riederer P, Braunewell KH (2002) The neuronal calcium sensor protein VILIP-1 is associated with amyloid plaques and extracellular tangles in Alzheimer’s disease and promotes cell death and tau phosphorylation in vitro: a link between calcium sensors and Alzheimer’s disease? Neurobiol. Dis. 8 (5): 900–9. PMID: 11592857

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Visinin-Like Protein 1 (VSNL1) Antibody
Western blot of rat cerebellar lysate showing specific immunolabeling of the ~22 kDa VSNL1 protein.

Click here to view our Western blotting and lysate preparation protocols.

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