Neuronal marker that works great in IHC!
- Protein G Purified
- Rat, Mouse, Human, Bovine
- WB 1:2,000IF 1: 500
- Mouse Monoclonal
- Gene Name:
- Molecular Reference:
- ~ 22 kDa
- Cite This Antibody:
- PhosphoSolutions Cat# 2145-VSNL1, RRID:AB_2492285
The antigen is recombinant full length human VSNL1 expressed in and purified from E. Coli.
The antibody is Protein G purified culture supernatant.
Biological Significance: ExpandCollapse
Visinin-like protein 1 (VSNL1), also known as VILIP1, is a calcium sensor protein expressed exclusively in neurons. Highest levels of VSNL1 expression are found in cerebellar Purkinje cells. VSNL1 has been implicated in the modulation of cell signaling cascades via regulation of adenyl cyclase activity (Braunewell et al., 1997). Additionally, VSNL1 has been associated with amyloid plaques and neurofibrillar tangles in Alzheimer’s disease (Schnurra et al., 2001).