Affinity purified from pooled serum. Learn more.

Tyrosine Hydroxylase Antibody, Sheep

Catalog #: 2027-THSHP Categories: , , , Datasheet:


  • SizePrice

Excellent neuronal marker for use in IHC!

Pooled Serum
Affinity Purified from Pooled Serum
Species Reactivity:
Most mammals, Some invertebrates
WB 1:1000IF 1:1000IHC 1:10
Sheep polyclonal
Gene Name:
Molecular Reference:
~60 kDa
Cite This Antibody:
PhosphoSolutions Cat# 2027-THSHP, RRID:AB_2492277
Antigen/Purification: ExpandCollapse

The antigen is a native rat tyrosine hydroxylase, purified from pheochromocytoma.

The antibody is prepared from sheep serum by affinity purification using a column to which immunogen was coupled. The antibody is predominantly of the IgG1 subclass.


Biological Significance: ExpandCollapse

Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001).

Synonyms: ExpandCollapse

• Dystonia 14 antibody
• DYT14 antibody
• DYT5b antibody
• EC antibody
• OTTHUMP00000011225 antibody
• OTTHUMP00000011226 antibody
• ple antibody
• Protein Pale antibody
• TH antibody
• The antibody
• TY3H_HUMAN antibody
• TYH antibody
• Tyrosine 3 hydroxylase antibody
• Tyrosine 3 monooxygenase antibody
• Tyrosine 3-hydroxylase antibody
• Tyrosine 3-monooxygenase antibody
• Tyrosine hydroxylase antibody


100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Product Specific References

Ryu, J.C., Tooke, K., Malley, S.E., Soulas, A., Weiss, T., Ganesh, N., Saidi, N., Daugherty, S., Saragovi, U., Ikeda, Y. and Zabbarova, I., 2018. Role of proNGF/p75 signaling in bladder dysfunction after spinal cord injury. The Journal of clinical investigation, May 1;128(5):1772-1786. PMID: 29584618

Zhu MY, Klimek V, Haycock JW, Ordway GA (2000) Quantitation of tyrosine hydroxylase protein in the locus coeruleus from postmortem human brain. J Neurosci Meth 99:37-44. PMID: 10936640


There are no reviews yet.

Be the first to review “Tyrosine Hydroxylase Antibody, Sheep”

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Tyrosine Hydroxylase Antibody, Sheep
Western blot of 10ug of rat striatal lysate showing specific immunolabeling of the ~60 kDa tyrosine hydroxylase protein.
Tyrosine Hydroxylase Antibody, Sheep
Immunostaining of rabbit retina showing specific labeling of tyrosine hydroxylase in green.

You may also like…