Testicular Receptor 4 (TR4) Antibody

Catalog #: 2004-TR4 Category: Datasheet:

$99.00$310.00

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Rabbit polyclonal antibody

Formulation:
Neat serum
Species Reactivity:
Rat, Mouse, Human
Applications:
WB 1:1000
Species:
Rabbit
Gene Name:
NR2C2
Molecular Reference:
~64 kDa
Cite This Antibody:
PhosphoSolutions Cat# 2004-TR4, RRID:AB_2492265
Antigen/Purification: ExpandCollapse

The antigen is a fusion protein of N-terminal peptide from mouse TR4.

The antibody is neat serum.

Biological Significance: ExpandCollapse

Testicular receptor 4 (TR4) is a member of the orphan nuclear receptor superfamily. Data suggests that TR4 may function as a regulator that modulates many signaling pathways. It has been suggested that TR4 is required for normal cerebellar development as TR4 knockout mice exhibit behavioral deficits in motor coordination (Chen, YT et al.,2008) and plays important roles in growth, embryonic and early postnatal survival (Collins, LL, et al., 2004).

Synonyms: ExpandCollapse

• hTAK1 antibody
• Nr2c2 antibody
• NR2C2_HUMAN antibody
• Nuclear hormone receptor TR4 antibody
• Nuclear receptor subfamily 2 group C member 2 antibody
• Orphan nuclear receptor TAK1 antibody
• Orphan nuclear receptor TR4 antibody
• TAK1 antibody
• Testicular nuclear receptor 4 antibody
• Testicular receptor 4 antibody
• TR2R1 antibody
• TR4 antibody
• TR4 nuclear hormone receptor antibody

Storage

100 µl neat serum. Adequate amount of material to conduct 10-mini Western Blots.

For long term storage –20° C is recommended in undiluted aliquots. Stable at –20° C for at least 1 year. Avoid freeze/thaw cycles.

Product Specific References

Tanabe O, Shen Y, Liu Q, Campbell AD, Kuroha T, Yamamoto M, Engel JD. “The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription.” Genes Dev. 2007, 21:2832-2844. PMID: 17974920

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Western blot of rat cerebellum lysate showing specific immunolabeling of the ~64 kDa TR4 protein.

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