Excellent neuronal axon marker!
- Formulation:
- Total IgY fraction
- Specificity:
- Rat, Human
- Applications:
- WB 1:10,000IF 1:1,000
- Species:
- Chicken Polyclonal
- Gene Name:
- MAPT
- Molecular Reference:
- ~48 kDa, ~65 kDa & ~75 kDa
- Cite This Antibody:
- PhosphoSolutions Cat# 1998-TAU, RRID:AB_2492256
Antigen/Purification: Collapse
The antigen is a recombinant full length human tau expressed in and purified from E. Coli.
The antibody is total IgY fraction.
Biological Significance: Collapse
Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985). Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990). Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer’s disease (AD), Pick’s disease and progressive supranuclear palsy.
