Tau Antibody

Catalog #: 1998-TAU Categories: , , Datasheet:

$99.00$310.00

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Excellent neuronal axon marker!

Formulation:
Total IgY fraction
Species Reactivity:
Rat, Human
Applications:
WB 1:10000IF 1:1000
Species:
Chicken Polyclonal
Gene Name:
MAPT
Molecular Reference:
~48 kDa, ~65 kDa & ~75 kDa
Cite This Antibody:
PhosphoSolutions Cat# 1998-TAU, RRID:AB_2492256
Antigen/Purification: ExpandCollapse

The antigen is a recombinant full length human tau expressed in and purified from E. Coli.

The antibody is total IgY fraction.

Biological Significance: ExpandCollapse

Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985). Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990). Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer’s disease (AD), Pick’s disease and progressive supranuclear palsy.

Synonyms: ExpandCollapse

• AI413597 antibody
• AW045860 antibody
• DDPAC antibody
• FLJ31424 antibody
• FTDP 17 antibody
• G protein beta1/gamma2 subunit interacting factor 1 antibody
• MAPT antibody
• MAPTL antibody
• MGC134287 antibody
• MGC138549 antibody
• MGC156663 antibody
• Microtubule associated protein tau antibody
• Microtubule associated protein tau isoform 4 antibody
• Microtubule-associated protein tau antibody
• MSTD antibody
• Mtapt antibody
• MTBT1 antibody
• MTBT2 antibody
• Neurofibrillary tangle protein antibody
• Paired helical filament tau antibody
• Paired helical filament-tau antibody
• PHF tau antibody
• PHF-tau antibody
• PPND antibody
• PPP1R103 antibody
• Protein phosphatase 1, regulatory subunit 103 antibody
• pTau antibody
• RNPTAU antibody
• TAU antibody
• TAU_HUMAN antibody
• Tauopathy and respiratory failure, included antibody

Storage

100 µl liquid containing 10 mM sodium azide. Adequate amount of material to conduct 10-mini Western Blots.

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

General References

Binder LI, Frankfurter A, Rebhun LI (1985) The distribution of tau in the mammalian central nervous system. J Cell Bio Oct; 101(4):1371-8.

Goedert M. and Jakes R. (1990) Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization. EMBO J 9, 4225-4230

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Tau Antibody
Western blot of rat cortical lysate showing specific immunolabeling of the ~48 kDa, ~65 kDa & ~75 kDa tau isoforms.
Immunofluorescence of cultured rat hippocampal neurons showing staining of tau in red along the neuronal processes.

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