Rabbit polyclonal antibodyPooled Serum
- 100 µl
- Affinity Purified from Pooled Serum
- Rat, Mouse, Human
- WB 1:1000IF 1:1,000IHC 1:1,000IP 5 µl per 200 µg lysate
- Molecular Reference:
- ~78 kDa
- Cite This Antibody:
- PhosphoSolutions Cat# 1926-SYNP, RRID:AB_2492242
The antigen is a native protein purified from bovine brain.
The antibody is prepared from pooled rabbit serum by affinity purification using a column to which the native protein was coupled.
Biological Significance: ExpandCollapse
Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002; Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation (Moore and Bernstein, 1989; Stone et al., 1994). Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogenesis is regulated by phosphorylation (Jovanovic et al., 2001; Kao et al., 2002).