Rabbit polyclonal antibody
- 100 µl
- Affinity purified
- Rat, Mouse, Human, Non-human primate, Rabbit, Guinea Pig
- WB 1:1,000IHC 1: 500
- Molecular Reference:
- ~24 kDa
- Cite This Antibody:
- PhosphoSolutions Cat# 1830-RBPMS, RRID:AB_2492225
The antigen is a synthetic peptide corresponding to amino acid residues from the N-terminal region of the rat RBPMS sequence conjugated to KLH.
The antibody is prepared from rabbit serum by affinity purification via chromatography on an affinity column prepared with the peptide used as antigen.
Biological Significance: ExpandCollapse
RBPMS (RNA binding protein with multiple splicing), also known as HERMES, contains one RRM (RNA recognition motif) domain and belongs to the RRM family of RNA-binding proteins. RBPMS exists as multiple alternatively spliced isoforms and is thought to bind RNA, possibly playing a role in RNA-related events, such as transcription and translation. RNA-binding proteins that are specific to retinal ganglion cells (RGCs) have been previously identified as excellent markers for RGCs (Kwong et al., 2010). Recent findings show that antibodies against RBPMS are robust reagents that exclusively identify RGCs in multiple mammalian species (Rodriguez et al. 2014)