Affinity purified from pooled serum. Learn more.

PSD-95 Antibody

We are the original manufacturer of our rabbit polyclonal PSD-95 antibody, affinity purified from pooled serum. It is excellent for use in WB.

Catalog #: 1080-PSD95 Categories: , , , , Datasheet:

$119.00$380.00

  • SizePrice
Clear
Pooled Serum
Formulation:
Affinity Purified from Pooled Serum
Species Tested:
Mouse, Rat
Expected Reactivity:
Bovine, Human, Non-Human Primate, Zebrafish
Applications:
WB 1:1000 Don't see your application?
Host Species:
Rabbit Polyclonal
Gene Name:
DLG4
Molecular Weight:
~95 kDa
Cite This Antibody:
PhosphoSolutions Cat# 1080-PSD95, RRID:AB_2492218
Antigen/Purification: ExpandCollapse

The antigen is a peptide corresponding to amino acid residues from the N-terminal region of rat PSD- 95, conjugated to keyhole limpet hemocyanin (KLH).

The antibody is prepared from rabbit serum by affinity purification via chromatography on an affinity column made with the N-terminal peptide used as antigen.

 

Biological Significance: ExpandCollapse

PSD-95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses (Kim and Sheng, 2004). Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation (Chung et al., 2004).

Synonyms: ExpandCollapse

• Discs large homolog 4 antibody
• Disks large homolog 4 antibody
• DLG 4 antibody
• Dlg4 antibody
• DLG4_HUMAN antibody
• FLJ97752 antibody
• FLJ98574 antibody
• Human post synaptic density protein 95 antibody
• Post synaptic density protein 95 antibody
• Postsynaptic density protein 95 antibody
• PSD 95 antibody
• PSD-95 antibody
• PSD95 antibody
• SAP 90 antibody
• SAP-90 antibody
• SAP90 antibody
• Synapse associated protein 90 antibody
• Synapse-associated protein 90 antibody
• Tax interaction protein 15 antibody

Storage

100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Product Specific Protocols

Western Blotting

Click here to view our protocols page for Western blotting and lysate preparation.

Product Specific References for Applications and Species

Western Blot: Rat


Western Blot: Rat
PMID Dilution Publication
29112734 1:1000 Duman, J.G., et al. 2018 Memantine prevents acute radiation-induced toxicities at hippocampal excitatory synapses. Neuro-oncology, 20(5), pp.655-665.

  • 5 – Excellent (publishable, performed ideally)
  • 4 – Good (publishable, would use again)
  • 3 – Average (publishable, might use again)
  • 2 – Poor (unpublishable, signal inconclusive)
  • 1 – No signal (unpublishable)
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