Mouse monoclonal antibody
- 100 µl
- Protein G Purified
- Rat, Mouse, Human, Bovine
- WB 1:2,000IF 1:500
- Mouse Monoclonal
- Molecular Reference:
- ~21 kDa
- Cite This Antibody:
- PhosphoSolutions Cat# 1597-Park7, RRID:AB_2492201
The antigen is a full length recombinant human park7 expressed in and purified from E. coli.
The antibody is Protein G purified from tissue culture supernatant.
Biological Significance: ExpandCollapse
Park7, also known as DJ-1, is a member of the peptidase C56 family of proteins and is thought to function as a molecular chaperone. Mutations in park7 have been associated with autosomal recessive, early onset Parkinson’s disease (Bonifati et al., 2003). Recently, park7 has been shown to inhibit microtubule associated protein 1B aggregation thus leading to neuronal apoptosis (Wang et al., 2011).