Mitochondrial marker that works great in IHC!
- Protein G Purified
- Human, Mouse, Rat
- WB 1:1000IF 1:500
- Mouse Monoclonal
- Molecular Reference:
- ~ 60 kDa
- Cite This Antibody:
- PhosphoSolutions Cat# 750-HSP60, RRID:AB_2715493
The antigen is recombinant full length human HSP60 protein.
The antibody is protein G purified from culture supernatant.
Biological Significance: ExpandCollapse
HSP60 is a member of the heat shock protein family which is thought to play a key role in mitochondrial protein transport and proper refolding of proteins imported from the cytoplasm into the mitochondrial matrix (Koll et al., 1992). More recently, HSP60 has been implicated in the pathogenesis of cardiovascular disease (Rizzo et al., 2011).