Affinity purified from pooled serum. Learn more.

GluR2 Antibody

Catalog #: 900-GluR2 Categories: , Datasheet:

$109.00$365.00

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Rabbit polyclonal antibody

Pooled Serum
Formulation:
Affinity Purified from Pooled Serum
Species Tested:
Rat
Expected Reactivity:
Mouse, Human, Chicken, Non-human primate, Zebra fish
Applications:
WB 1:1000 Don't see your application?
Species:
Rabbit
Gene Name:
GRIA2
Molecular Weight:
~100 kDa
Cite This Antibody:
PhosphoSolutions Cat# 900-GluR2, RRID:AB_2492129
Antigen/Purification: ExpandCollapse

The antigen is a peptide corresponding to amino acid residues from rat GluR2, conjugated to keyhole limpet hemocyanin (KLH).

The antibody is prepared from pooled rabbit serum by affinity purification on a column made with the peptide antigen.

Biological Significance: ExpandCollapse

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990;Hollmann and Heinemann, 1994). The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD (Chung et al., 2003).

Synonyms: ExpandCollapse

• AMPA 2 antibody
• AMPA selective glutamate receptor 2 antibody
• AMPA-selective glutamate receptor 2 antibody
• AMPA2 antibody
• GluA2 antibody
• GLUR 2 antibody
• GLUR B antibody
• GluR K2 antibody
• GluR-2 antibody
• GluR-B antibody
• GluR-K2 antibody
• GLUR2 antibody
• GLURB antibody
• Glutamate receptor 2 antibody
• Glutamate receptor ionotropic AMPA 2 antibody
• Glutamate receptor ionotropic antibody
• Gria2 antibody
• GRIA2_HUMAN antibody
• HBGR2 antibody

Storage

100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Product Specific Protocols

Western Blotting

Click here to view our protocols page for Western blotting and lysate preparation.

Product Specific References for Applications and Species

Western Blot: Rat


Western Blot: Rat
PMID Dilution Publication
29432883 not listed Mao, M., et al. 2018 Regulation of Phosphorylation of AMPA Glutamate Receptors by Muscarinic M4 Receptors in the Striatum In vivo. Neuroscience, 375, pp.84-93.
28578480 not listed Lameth, J., et al. 2017 Acute Neuroinflammation Promotes Cell Responses to 1800 MHz GSM Electromagnetic Fields in the Rat Cerebral Cortex. Neurotoxicity Research, pp.1-16.
25689263 1:1000 Mao, L.M., et al. 2015 Dynamic increases in AMPA receptor phosphorylation in the rat hippocampus in response to amphetamine. Journal of neurochemistry, 133(6), pp.795-805.
24231469 1:1000 Xue, B., et al. 2015 Rapid and sustained GluA1 S845 phosphorylation in synaptic and extrasynaptic locations in the rat forebrain following amphetamine administration. Neurochemistry international, 64, pp.48-54.

  • 5 – Excellent (publishable, performed ideally)
  • 4 – Good (publishable, would use again)
  • 3 – Average (publishable, might use again)
  • 2 – Poor (unpublishable, signal inconclusive)
  • 1 – No signal (unpublishable)
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