Mouse monoclonal antibody
- 100 µl
- Protein G Purified
- Rat, Mouse
- WB 1:1,000
- Gene Name:
- Molecular Reference:
- ~105 kDa
- Cite This Antibody:
- PhosphoSolutions Cat# 895-GluR1, RRID:AB_2492126
The antigen is a peptide corresponding to amino acid residues from the N-terminal region of rat GluR1.
The antibody is protein G purified culture supernatant.
Biological Significance: ExpandCollapse
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990;Hollmann and Heinemann, 1994).