GluR1 Antibody

Catalog #: 895-GLUR1 Category: Datasheet:

$365.00

Mouse monoclonal antibody

Size:
100 µl
Formulation:
Protein G Purified
Specificity:
Rat, Mouse
Applications:
WB 1:1,000
Species:
Mouse
Gene Name:
GRIA1
Molecular Reference:
~105 kDa
Cite This Antibody:
PhosphoSolutions Cat# 895-GluR1, RRID:AB_2492126
Antigen/Purification: ExpandCollapse

The antigen is a peptide corresponding to amino acid residues from the N-terminal region of rat GluR1.

The antibody is protein G purified culture supernatant.

Biological Significance: ExpandCollapse

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990;Hollmann and Heinemann, 1994).

Storage

100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.

For long term storage –20° C is recommended. Stable at –20° C for at least 1 year.

Product Specific References

Lameth, J., Gervais, A., Colin, C., Lévêque, P., Jay, T.M., Edeline, J.M. and Mallat, M., 2017. Acute Neuroinflammation Promotes Cell Responses to 1800 MHz GSM Electromagnetic Fields in the Rat Cerebral Cortex. Neurotoxicity Research, pp.1-16. PMID: 28578480

Shen Y, Fu WY, Cheng EY, Fu AK, and Ip NY (2013) Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanism.J Neurosci. 33(2):464-72. PMID: 23303927.

GluR1 Antibody
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~105 kDa GluR1 protein.

You may also like…