Affinity purified from pooled serum. Learn more.

GABAB R1 (Ser923) Antibody

We are the original manufacturer of our GABAB R1 (Ser923) rabbit polyclonal phosphospecific antibody, affinity purified from pooled serum. Optimized in WB.

Catalog #: p1148-923 Categories: , Datasheet:

$119.00$380.00

  • SizePrice
Clear
Pooled Serum
Formulation:
Affinity Purified from Pooled Serum
Species Tested:
Mouse, Rat
Expected Reactivity:
Bovine, Human, Non-human primate
Applications:
WB 1:1000 Don't see your application?
Host Species:
Rabbit Polyclonal
Gene Name:
GABBR1
Molecular Weight:
~102 kDa
Cite This Antibody:
PhosphoSolutions Cat# p1148-923, RRID:AB_2492118
Antigen/Purification: ExpandCollapse

The antigen is a phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser923 of GABAB R1.

The antibody is prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho- and dephospho-peptide affinity columns.

Biological Significance: ExpandCollapse

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABAreceptor effector coupling (Couve et al., 2004). Phosphorylation of Ser923 is thought to be important in the regulation of GABAB receptor function.

Synonyms: ExpandCollapse

• dJ271M21.1.1 antibody
• dJ271M21.1.2 antibody
• FLJ92613 antibody
• GABA-B receptor 1 antibody
• GABA-B-R1 antibody
• GABA-BR1 antibody
• GABAB R1 antibody
• GABAB subunit 1c antibody
• GABABR1 antibody
• GABBR1 3 antibody
• GABBR1 antibody
• GABR1_HUMAN antibody
• Gamma aminobutyric acid (GABA) B receptor 1 antibody
• Gamma-aminobutyric acid type B receptor subunit 1 antibody
• Gb1 antibody
• GPRC3A antibody
• Seven transmembrane helix receptor antibody

Storage

100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Product Specific Protocols

Western Blotting

Click here to view our protocols page for Western blotting and lysate preparation.

General References

Couve A, Calver AR, Fairfax B, Moss SJ, Pangalos MN (2004) Unraveling the unusual signaling properties of the GABA(B) receptor. Biochem. Pharmacol. Oct 15;68(8):1527-36. PMID: 15451395

  • 5 – Excellent (publishable, performed ideally)
  • 4 – Good (publishable, would use again)
  • 3 – Average (publishable, might use again)
  • 2 – Poor (unpublishable, signal inconclusive)
  • 1 – No signal (unpublishable)
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