Affinity purified from pooled serum. Learn more.

Dopamine β-Hydroxylase Antibody, C-Terminus

Catalog #: 420-DBHC Categories: , , , Datasheet:

$109.00$365.00

  • SizePrice
Clear

Sheep polyclonal antibody

Pooled Serum
Formulation:
Affinity Purified from Pooled Serum
Species Reactivity:
Mouse, Human, Non-human primate
Applications:
WB 1:1000
Species:
Sheep
Gene Name:
DBH
Molecular Reference:
~75 kDa
Cite This Antibody:
PhosphoSolutions Cat# 420-DBHC, RRID:AB_2492074
Antigen/Purification: ExpandCollapse

The antigen is a peptide from the C-terminal region of human dopamine ?-hydroxylase (DBH), conjugated to keyhole limpet hemocyanin (KLH).

The antibody is prepared from pooled sheep serum by affinity purification using a Sulfo-Link® column matrix to which the peptide immunogen was coupled.

Biological Significance: ExpandCollapse

DBH catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. DBH antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). The expression of DBH is also elevated during stress (Sabban and Kvetnansky, 2001).

Synonyms: ExpandCollapse
  • dbh antibody
  • DBM antibody
  • Dopamine beta hydroxylase antibody
  • Dopamine beta monooxygenase antibody
  • Dopamine beta-hydroxylase (dopamine beta-monooxygenase) antibody
  • Dopamine beta-monooxygenase antibody
  • DOPO_HUMAN antibody
  • OTTHUMP00000022501 antibody
  • Soluble dopamine beta-hydroxylase antibody

Storage

100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Product Specific References

Zhu MY, Klimek V, Haycock JW, Ordway GA (2000) Quantitation of tyrosine hydroxylase protein in the locus coeruleus from postmortem human brain. J Neurosci Meth 99:37-44. PMID: 10936640

Reviews

There are no reviews yet.

Be the first to review “Dopamine β-Hydroxylase Antibody, C-Terminus”

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Dopamine β-Hydroxylase Antibody, C-Terminus
Western blot of human adrenal medulla lysate showing specific immunolabeling of the ~75 kDa DBH protein.

You may also like…