Collagen I, alpha 1, propeptide Antibody

The antigen is a peptide from the human collagen I ?1 propeptide sequence.

The antibody is affinity purified.

Collagen is an extracellular matrix protein that serves as a scaffold defining the shape and mechanical properties of many tissues and organs including skin, tendon, artery walls, fibrocartilage, bone and teeth. Type 1 collagen is the most abundant protein in mammals. Collagens are synthesized with N-terminal and C-terminal propeptides that are cleaved during maturation and secretion. After cleavage of the propeptides, the most N-terminal and C-terminal remaining sequences are known as telopeptides. Mutations in the collagen 1, alpha 1 gene (COL1A1) are known to cause osteogenesis imperfecta (aka brittle bone disease) (Byers 1989). Furthermore, mutations found in the first 90 residues of the helical region of alpha 1 collagen have been implicated in the prevention or delayed removal of the procollagen N-propeptide leading to a combined osteogenesis imperfecta and Ehlers-Danlos syndrome (EDS) phenotype (Cabral et al., 2005)

• Alpha 1 type I collagen antibody
• Alpha 2 type I collagen antibody
• alpha 2 type I procollagen antibody
• alpha 2(I) procollagen antibody
• alpha 2(I)-collagen antibody
• Alpha-1 type I collagen antibody
• alpha1(I) procollagen antibody
• CO1A1_HUMAN antibody
• COL1A1 antibody
• COL1A2 antibody
• collagen alpha 1 chain type I antibody
• Collagen alpha-1(I) chain antibody
• collagen alpha-1(I) chain preproprotein antibody
• Collagen I alpha 1 polypeptide antibody
• Collagen I alpha 2 polypeptide antibody
• collagen of skin, tendon and bone, alpha-1 chain antibody
• collagen of skin, tendon and bone, alpha-2 chain antibody
• Collagen type I alpha 1 antibody
• Collagen type I alpha 2 antibody
• EDSC antibody
• OI1 antibody
• OI2 antibody
• OI3 antibody
• OI4 antibody
• pro-alpha-1 collagen type 1 antibody
• type I proalpha 1 antibody
• type I procollagen alpha 1 chain antibody
• Type I procollagen antibody