Great marker for oligodendrocytes and Schwann cells!
- Size:
- 50 µl
- Formulation:
- Neat serum
- 100% Homology:
- Rat, Mouse, Human, Sheep, Rabbit
- Applications:
- WB 1:1,000IHC 1:1,000
- Species:
- Rabbit polyclonal
- Gene Name:
- CNP
- Molecular Reference:
- ~46 kDa
- Cite This Antibody:
- PhosphoSolutions Cat# 327-CON, RRID:AB_2492063
Antigen/Purification: Collapse
The antigen is an endogenous rabbit 2,3-cyclic nucleotide-3-phospho-diesterase.
The antibody is neat serum.
Biological Significance: Collapse
2,3-cyclic nucleotide-3-phosphodiesterase (CNP) is a membrane bound, microtubule associated protein that is among the most abundant myelin proteins of the CNS. It is thought that CNP may serve as a regulator of tubulin polymerization and of microtubule distribution (Bifulco et al., 2002). It was recently found that CNP may also function as a possible linker protein anchoring microtubules to the plasma membrane via a 13 residue C-terminal CNP fragment (Bifulco et al., 2002, Esposito et al., 2008).
