Anti-CaM Kinase II (Thr286) Antibody

Our Anti-CaM Kinase II (Thr286) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, rabbit, and rat CaM Kinase II (Thr286) and is antigen affinity purified from pooled serum. It is great for use in WB, IHC.



SKU: p1005-286

Volume: 100 µL
Price:
Sale price$430

Product Specific References for Applications and Species

Immunocytochemistry: Human
PMID Dilution Publication
26057350 not listed Samikkannu, T., et al. 2015. HIV subtypes B and C gp120 and methamphetamine interaction: dopaminergic system implicates differential neuronal toxicity. Scientific reports, 5, p.11130.
Immunocytochemistry: Rat
PMID Dilution Publication
32492405 not listed Li, B., et al. 2020. Neuronal Inactivity Co-opts LTP Machinery to Drive Potassium Channel Splicing and Homeostatic Spike Widening. Cell, S0092-8674(20), p.p. 30575-4.
Immunohistochemistry: Rabbit
PMID Dilution Publication
22593045 1:1000 Kothmann, W.W., et al. 2012. Nonsynaptic NMDA Receptors Mediate Activity-Dependent Plasticity of Gap Junctional Coupling in the All Amacrine Cell Network. J. Neurosci. 32(3): 6747-6759.
Western Blot: Human
PMID Dilution Publication
379071401:1000Castellanos, LCS, et al. 2023. Redistribution of ASIC1a channels triggered by IL-6: Potential role of ASIC1a in neuroinflammation. Biochimica et biophysica acta. Molecular basis of disease, 166927.
30143647 1:1000 Lee, S.H., et al. 2018. Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes. Nature communications, 9(1), p.3434.
28318784 not listed Murakoshi, H., et al. 2017. Kinetics of Endogenous CaMKII Required for Synaptic Plasticity Revealed by Optogenetic Kinase Inhibitor. Neuron. Apr 5;94(1):37-47.e5.
26057350 not listed Samikkannu, T., et al. 2015. HIV subtypes B and C gp120 and methamphetamine interaction: dopaminergic system implicates differential neuronal toxicity. Scientific reports, 5, p.11130.
24855644 1:3000 Coultrap, S.J., et al. 2014. Nitric oxide induces Ca2+-independent activity of the Ca2+/calmodulin-dependent protein kinase II (CaMKII). J. Biol Chem. 289(28):19458-65.
23255606 1:10,000 Magupalli, V.G., et al. 2013. Ca2+-independent activation of Ca2+/calmodulin-dependent protein kinase II bound to the C-terminal domain of CaV2. 1 calcium channels. Journal of Biological Chemistry, 288(7), 4637-4648.
Western Blot: Mouse
PMID Dilution Publication
379071401:1000Castellanos, LCS, et al. 2023. Redistribution of ASIC1a channels triggered by IL-6: Potential role of ASIC1a in neuroinflammation. Biochimica et biophysica acta. Molecular basis of disease, 166927.
376488531:2500Tullis, JE, et al. 2023. LTP induction by structural rather than enzymatic functions of CaMKII. Nature, 146-153.
349654141:2000Buonarati, O.R., et al. 2021. Conserved and Divergent Features of Neuronal CaMKII Holoenzyme Structure, Function, and High-Order Assembly. Cell Reports, 110168.
347040021:2500Tullis, J.E., et al. 2021. GluN2B S1303 Phosphorylation by CaMKII or DAPK1: No Indication for Involvement in Ischemia or LTP. iScience, 103214.
33881939 1:2000 Goodell, D.J., et al. 2021. Young DAPK1 knockout mice have altered presynaptic function. Journal of Neurophysiology, 125(5), pp1973-1981.
33853773 1:1000 Cook, S.G., et al. 2021. CaMKII holoenzyme mechanisms that govern the LTP versus LTD decision. Science Advances, 7(16), p.eabe2300.
33449853 1:1000 Kreitmeier, K.G., et al. 2021. CaMKIIδ Met281/282 oxidation is not required for recovery of calcium transients during acidosis. American Journal of Physiology-Heart and Circulatory Physiology, January 15.
31914378 1:2500 Buonarati, O.R., et al. 2020. CaMKII versus DAPK1 Binding to GluN2B in Ischemic Neuronal Cell Death after Resuscitation from Cardiac Arrest. Cell Reports, 30(1), pp.1-8.
30282026 1:1000 Glasgow, S.D., et al. 2018. Activity-dependent netrin-1 secretion drives synaptic insertion of GluA1-containing AMPA receptors in the hippocampus. Cell Rep, 25(1):168-182.
27622724 not listed Huang, L., et al. 2017. Long-lasting behavioral effects in neonatal mice with multiple exposures to ketamine-xylazine anesthesia. Neurotoxicology and Teratology.
18417701 1:10,000 Sun, X., et al. 2008. Acute and Chronic Dopamine Receptor Stimulation Modulates AMPA Receptor Trafficking in Nucleus Accumbens Neurons Cocultured with Prefrontal Cortex Neurons. J. Neurosci., 28: 4216 - 4230.
17855343 not lited Townsend, M., et al. 2008. Soluble A-beta Inhibits Specific Signal Transduction Cascades Common to the Insulin Receptor Pathway. J. Biol. Chem., 282: 33305 - 33312.
Western Blot: Rat
PMID Dilution Publication
36331254not listedKazami, M., et al. 2022. Ca2+/Calmodulin induces translocation of membrane-associated TSC2 to the nucleus where it suppresses CYP24A1 expression. Bioscience, Biotechnology, and Biochemistry, zbac174.
356204301:2500Brown, C.N., et al. 2022. Aβ-induced Synaptic Impairments Require CaMKII Activity That is Stimulated by Indirect Signaling Events. iScience, 104368.
34687697 1:1000 Rumian, N.L., et al. 2021. CaMKIIα knockout protects from ischemic neuronal cell death after resuscitation from cardiac arrest. Brain Research, 1773, p147699.
34667946not listedBrown, C.N., et al. 2021. Characterization of Six CaMKIIα Variants Found in Patients with Schizophrenia. iScience, 103184.
34544759 1:1000 Murray, C.H., et al. 2021. CaMKII Modulates Diacylglycerol Lipase-α Activity in the Rat Nucleus Accumbens after Incubation of Cocaine Craving. eNeuro, 8(5).
33444640 1:1000 Murray, C.H., et al. 2021. mGlu5 function in the nucleus accumbens core during the incubation of methamphetamine craving. Neuropharmacology, p.108452.
30143647 1:1000 Lee, S.H., et al. 2018. Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes. Nature communications, 9(1), p.3434.
28318784 not listed Murakoshi, H., et al. 2017. Kinetics of Endogenous CaMKII Required for Synaptic Plasticity Revealed by Optogenetic Kinase Inhibitor. Neuron. Apr 5;94(1):37-47.e5.
24843070 1:3000 Barcomb, K., et al. 2014. Autonomous CaMKII requires further stimulation by Ca2+/calmodulin for enhancing synaptic strength. The FASEB Journal, 28(8), 3810-3819.
24780380 1:2000 Bernard, P.B., et al. 2014. Necessary, but not sufficient: insights into the mechanisms of mGluR mediated long-term depression from a rat model of early life seizures. Neuropharmacology, 84, 1-12.
23143515 1:1000 Shin, S.M., et al. 2012. GKAP orchestrates activity-dependent postsynaptic protein remodeling and homeostatic scaling. Nature neuroscience, 15(12), p.1655-1666.
20424167 not listed Vest, R.S., et al. 2010. Dual Mechanism of a Natural CaMKII Inhibitor. Mol. Biol. Cell, 18: 5024-5033.
20353941 not listed Coultrap, S.J., et al. 2010. CaMKII Autonomy Is Substrate-dependent and Further Stimulated by Ca2+/Calmodulin. J. Biol. Chem., 285: 17930 - 17937.
18819923 1:1000 Davies, K.D., et al. 2008. Long Term Synaptic Depression That Is Associated with GluR1 Dephosphorylation but Not Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Internalization. J. Biol. Chem., 283: 33138 - 33146.
18417701 1:10,000 Sun, X., et al. 2008. Acute and Chronic Dopamine Receptor Stimulation Modulates AMPA Receptor Trafficking in Nucleus Accumbens Neurons Cocultured with Prefrontal Cortex Neurons. J. Neurosci., 28: 4216 - 4230.
17942605 1:500 Sun, X., et al. 2008. Dual Mechanism of a Natural CaMKII Inhibitor. Mol. Biol. Cell, 18: 5024 - 5033.

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