Excellent for use in IHC!
- Formulation:
- Protein G purified
- 100% Homology:
- Rat, Mouse, Human, Non-human primate
- Applications:
- WB 1:1,000IF 1:500 IHC 1:500
- Species:
- Sheep polyclonal
- Gene Name:
- CALB2
- Molecular Reference:
- ~29 kDa
- Cite This Antibody:
- PhosphoSolutions Cat# 303-CAL, RRID:AB_2492050
Antigen/Purification: Collapse
The antigen is a purified guinea pig calretinin.
The antibody is protein A purified sheep serum.
Biological Significance: Collapse
Calretinin is a calcium-binding protein involved in calcium signaling. It is abundantly expressed throughout the central nervous system, retina and many other tissues. Studies have shown that calretinin may play a role in neuroprotection by buffering intracellular calcium (Lukas and Jones 1994, Weisenhorn et al., 1996). Additionally, calretinin selectively stains mesothelial cells thus making it an important marker for differentiating malignant mesothelioma from carcinomas (Attanoos et al., 2000).
