Name: Anti-Tau Antibody
Brand: PhosphoSolutions
SKU: 1998-TAU
Price: 415.0 USD
Availability: InStock

Our Anti-Tau primary antibody from PhosphoSolutions is chicken polyclonal. It detects bovine, human, mouse, pig, and rat Tau and is total IgY fraction. It is great for use in WB, IHC, ICC.

Product Type

Primary Antibody

Species Reactivity

Human, Rat

Applications

ICC, IHC, WB

Host Species

Chicken

Format

Total IgY fraction

Gene Name

MAPT

Go to Full Product Details

Western blot of rat cortical lysate showing specific immunolabeling of the ~48 kDa, ~65 kDa & ~75 kDa tau isoforms.

Immunostaining of cultured E20 rat cortical neurons and glia stained with anti-TAU antibody (cat. 1998-TAU, green, 1:2000) and anti-MAP2 (red). The blue is DAPI staining nuclear DNA. Anti-TAU labels perikarya, dendrites, axons of neurons while anti-MAP2 only labels dendrites and perikarya of neurons. Where they overlap they appear orange-yellow.

Immunostaining of cultured rat hippocampal neurons stained with anti-TAU antibody (cat. 1998-TAU, red, 1:1000) along the neuronal processes.

Western blot of rat cortical lysate showing specific immunolabeling of the ~48 kDa, ~65 kDa & ~75 kDa tau isoforms.

Volume: 100 µL

Variant

Price:

$415

Quantity:

Bulk Order Anti-Tau Antibody

Product Details

Target

Tau

Target Description

Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985). Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990). Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer’s disease (AD), Pick’s disease and progressive supranuclear palsy.

Format

Total IgY fraction

Clonality

Polyclonal

Isotype

IgY

Applications

ICC, IHC, WB

Host Species

Chicken

Gene Name

MAPT

Antigen

Recombinant full length human tau expressed in and purified from E.Coli.

Species Reactivity

Human, Rat

Antibody Registry ID

AB_2492256

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Production Notes

Total IgY fraction.

Buffer

PBS + 10 mM NaN3.

Dilution Ranges

WB: 1:10000
WB Brain: 1:10000
IHC: 1:1000
ICC: 1:1000-1:2000

Conjugate

Unconjugated

Specificity

Specific for the ~48, 65 & 75 kDa tau isoforms.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

AI413597 antibody, AW045860 antibody, DDPAC antibody, FLJ31424 antibody, FTDP 17 antibody, G protein beta1/gamma2 subunit interacting factor 1 antibody, MAPT antibody, MAPTL antibody, MGC134287 antibody, MGC138549 antibody, MGC156663 antibody, Microtubule associated protein tau antibody, Microtubule associated protein tau isoform 4 antibody, Microtubule-associated protein tau antibody, MSTD antibody, Mtapt antibody, MTBT1 antibody, MTBT2 antibody, Neurofibrillary tangle protein antibody, Paired helical filament tau antibody, Paired helical filament-tau antibody, PHF tau antibody, PHF-tau antibody, PPND antibody, PPP1R103 antibody, Protein phosphatase 1 regulatory subunit 103 antibody, pTau antibody, RNPTAU antibody, TAU antibody, TAU_HUMAN antibody, Tauopathy and respiratory failure included antibody

UniProt Details

UniProt (Human): P10636
UniProt (Immunogen Species): P10636

NCBI Gene ID

4137

Product Specific References for Applications and Species

Immunocytochemistry: Human
Immunohistochemistry: Human

Immunocytochemistry: Human
PMID	Dilution	Publication
37773257	1:1000	Agarwal, D, et al. 2023. Human retinal ganglion cell neurons generated by synchronous BMP inhibition and transcription factor mediated reprogramming. NPJ Regenerative medicine, 55.

Immunohistochemistry: Human
PMID	Dilution	Publication
33382979	1:1000	Zhang, K.Y., et al. 2020. Role of the Internal Limiting Membrane in Structural Engraftment and Topographic Spacing of Transplanted Human Stem Cell-Derived Retinal Ganglion Cells. Stem Cell Reports,16(1),149-167.

Product Specific Protocols

Tau Cultured Rat Hippocampal Neurons ICC Protocol: Download

Tau Cultured E20 Rat Cortical Neuron/Glia Cultures ICC Protocol: Download

Western Blot Protocol: Download

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Anti-Tau Antibody

Our Anti-Tau primary antibody from PhosphoSolutions is chicken polyclonal. It detects bovine, human, mouse, pig, and rat Tau and is total IgY fraction. It is great for use in WB, IHC, ICC.