Name: Anti-Syntaxin Antibody
Brand: PhosphoSolutions
SKU: 1990-STX
Price: 415.0 USD
Availability: InStock

Our Anti-Syntaxin primary antibody from PhosphoSolutions is mouse monoclonal. It detects human, rat, pig, and hamster Syntaxin and is Protein G purified. It is great for use in WB, IHC.

Product Type

Primary Antibody

Species Reactivity

Hamster, Human, Pig, Rat

Clone

SP8

Applications

IHC, WB

Host Species

Mouse

Format

Protein G Purified

Gene Name

STX1A

Molecular Weight

36 kDa

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Western blot of rat cortical lysate showing specific immunolabeling of the ~ 36 kDa syntaxin 1A protein.

Volume: 100 µL

Variant

Price:

$415

Quantity:

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Product Details

Target

Syntaxin

Target Description

Syntaxins are a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion (Khvotchev et al., 2007). Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have recently been correlated with schizophrenia (Castillo et al., 2010).

Format

Protein G Purified

Clonality

Monoclonal

Clone

SP8

Isotype

IgG1

Applications

IHC, WB

Host Species

Mouse

Gene Name

STX1A

Molecular Weight

36 kDa

Antigen

Synaptic immunoprecipitate (crude) from human brain.

Species Reactivity

Hamster, Human, Pig, Rat

Antibody Registry ID

AB_2492254

Storage

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Physical State

Liquid

Production Notes

Protein G purified culture supernatant.

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Dilution Ranges

WB: 1:1000
WB Brain: 1:1000
IHC: 1:100

Conjugate

Unconjugated

Specificity

Specific for endogenous levels of the ~36 kDa syntaxin protein. The antibody has also been used for immunohistochemistry on formalin fixed, vibratome sections. *Does not work on paraffin sections.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

HPC 1 antibody, Neuron specific antigen HPC1 antibody, Neuron-specific antigen HPC-1 antibody, OTTHUMP00000174615 antibody, OTTHUMP00000174616 antibody, OTTHUMP00000174617 antibody, OTTHUMP00000174618 antibody, P35-1 antibody, STX1 antibody, STX1A antibody, STX1A_HUMAN antibody, SYN1A antibody, Syntaxin 1A (brain) antibody, Syntaxin 1A brain antibody, Syntaxin-1A antibody

UniProt Details

UniProt (Human): Q16623
UniProt (Immunogen Species): Q16623

NCBI Gene ID

6804

Product Specific References for Applications and Species

Immunohistochemistry: Mouse

Immunohistochemistry: Mouse
PMID	Dilution	Publication
30640971	1:100	Blandford, S.N., et al. 2019. Retinal Characterization of the Thy1-GCaMP3 Transgenic Mouse Line After Optic Nerve Transection. Investigative Ophthalmology and Visual Science, 60(1), pp.183-191.

Product Specific Protocols

Western Blot Protocol: Download

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Anti-Syntaxin Antibody (SP8)

Our Anti-Syntaxin primary antibody from PhosphoSolutions is mouse monoclonal. It detects human, rat, pig, and hamster Syntaxin and is Protein G purified. It is great for use in WB, IHC.

Anti-Syntaxin Antibody
SKU: 1990-STX

Bulk Order Anti-Syntaxin Antibody

Product Details

Product Specific References for Applications and Species

Product Specific Protocols

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Anti-Syntaxin Antibody (SP8)

Our Anti-Syntaxin primary antibody from PhosphoSolutions is mouse monoclonal. It detects human, rat, pig, and hamster Syntaxin and is Protein G purified. It is great for use in WB, IHC.

Anti-Syntaxin Antibody SKU: 1990-STX

Bulk Order Anti-Syntaxin Antibody

Product Details

Product Specific References for Applications and Species

Product Specific Protocols

Anti-Syntaxin Antibody
SKU: 1990-STX