Anti-Syntaphilin (N-terminal region) Antibody (M371)

Name: Anti-Syntaphilin (N-terminal region) Antibody
Brand: PhosphoSolutions
SKU: SM3711
Price: 255.0 USD
Availability: InStock

from PhosphoSolutions

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

M371

Applications

Host Species

Mouse

Format

Protein A Purified

Gene Name

SNPH

Molecular Weight

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Western blot of adult mouse brain lysate. The blot was probed with mouse monoclonal anti-Syntaphilin (N-terminal region) antibody at 1:250 (lane 1), 1:1000 (lane 2), or 1:2000 (lane 3).

Volume: 100 µL

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Target

Syntaphilin (N-terminal region)

Target Description

Synaptic vesicles are organelles situated at the distal terminus of the presynaptic neuron. The exocytosis of these vesicles requires docking at the plasma membrane, priming, and fusion. Fusion is mediated by a complex consisting of membrane components of both the synaptic vesicle and the synaptic plasma membrane. The fusion complex consists of the soluble NSF (N-ethyl-maleimide-sensitive factor), SNAPs (soluble NSF attachment proteins), and receptor proteins (SNAREs) that include synaptobrevin, synaptotagmin, syntaxin, and SNAP-25 (synaptosomal-associated protein of 25kDa). Syntaxin-1 is a key component of the synaptic vesicle docking/fusion machinery which forms the SNARE complex with SNAP-25 and synaptobrevin. Syntaphilin is a brain-specific membrane-associated protein that can inhibit SNARE complex formation by binding free syntaxin-1.

Format

Protein A Purified

Clonality

Monoclonal

Clone

M371

Isotype

IgG1

Applications

Host Species

Mouse

Gene Name

SNPH

Molecular Weight

Antigen

Clone M371 was generated from a sequence corresponding to amino acids in the N-terminal region of human syntaphilin. This sequence has high homology to mouse and rat syntaphilin.

Species Reactivity

Human, Mouse, Rat

Storage

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Physical State

Liquid

Buffer

PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol

Dilution Ranges

WB: 1:500

Conjugate

Unconjugated

Specificity

This antibody detects a 70 kDa* protein corresponding to the molecular mass of Syntaphilin on SDS-PAGE immunoblots of adult mouse brain.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

SNPH

UniProt Details

UniProt (Human): O15079
UniProt (Immunogen Species): O15079

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Anti-Syntaphilin (N-terminal region) Antibody (M371)

Anti-Syntaphilin (N-terminal region) Antibody
SKU: SM3711

Bulk Order Anti-Syntaphilin (N-terminal region) Antibody

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Anti-Syntaphilin (N-terminal region) Antibody SKU: SM3711

Bulk Order Anti-Syntaphilin (N-terminal region) Antibody

Product Details

Anti-Syntaphilin (N-terminal region) Antibody
SKU: SM3711