Anti-Survivin Antibody

Name: Anti-Survivin Antibody
Brand: PhosphoSolutions
SKU: 24283
Price: 415.0 USD
Availability: InStock

from PhosphoSolutions

Our Survivin rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat Survivin and is antigen affinity purified. It is great for use in WB.

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Applications

Host Species

Rabbit

Format

Antigen Affinity Purified

Gene Name

BIRC5

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Title: 100 µL

Variant

Price:

$415

Quantity:

Bulk Order Anti-Survivin Antibody

Product Details

Target

Survivin

Target Description

Survivin is a human gene encoding a structurally unique IAP apoptosis inhibitor. Present during fetal development, survivin is undetectable in terminally differentiated adult tissues. However, survivin becomes prominently expressed in transformed cell lines and in all the most common human cancers of lung, colon, pancreas, prostate and breast, in vivo. Survivin is also found in high-grade non-Hodgkin's lymphomas. These data suggest that apoptosis inhibition may be a general feature of neoplasia and identify survivin as a potential new target for apoptosis-based therapy in cancer and lymphoma.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

Host Species

Rabbit

Gene Name

BIRC5

Antigen

Synthetic peptide corresponding to amino acids from the C-terminal region of human Survivin protein.

Species Reactivity

Human, Mouse, Rat

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with the C-terminal region of the human, mouse and rat Survivin protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

BIRC5, Baculoviral IAP repeat-containing protein 5, Apoptosis inhibitor 4

UniProt Details

UniProt (Human): O15392
UniProt (Immunogen Species): O15392

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Anti-Survivin Antibody

Our Survivin rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat Survivin and is antigen affinity purified. It is great for use in WB.