Anti-Sphingosine Kinase 1 (Ser-225), Phosphospecific Antibody

Our Sphingosine Kinase 1 (Ser-225) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects human Sphingosine Kinase 1 (Ser-225) and is antigen affinity purified. It is great for use in WB.



SKU: SP1641

Volume: 100 µL
Price:
Sale price$329

Product Specific References for Applications and Species

Immunocytochemistry: Human
PMID Dilution Publication
34873055not listedMolinar-Inglis, O, et al. 2021. aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete, β-arrestin-2-mediated SphK1-S1PR1-Akt signaling axis. Proceedings of the National Academy of Sciences of the United States of America, e2106623118.
Immunocytochemistry: Mouse
PMID Dilution Publication
32771459not listedRanasinghe, ADCU, et al. 2020. Mechanistic regulation of SPHK1 expression and translocation by EMAP II in pulmonary smooth muscle cells. Biochimica et biophysica acta. Molecular and cell biology of lipids, 158789.
Immunohistochemistry: Human
PMID Dilution Publication
376483311:100Nagaro, H, et al. 2023. Clinical Significance of Phosphorylated Sphingosine Kinase 1 Expression in Pancreatic Ductal Adenocarcinoma. Anticancer Research, 3969-3977.
305274631:100Nemoto, M, et al. 2019. Phospho-Sphingosine Kinase 1 Expression in Lymphatic Spread of Esophageal Squamous Cell Carcinoma. The journal of surgical research, 123-131.
302789481:100Yuza, K, et al. 2018. Upregulation of phosphorylated sphingosine kinase 1 expression in colitis-associated cancer. The journal of surgical research, 323-330.
293709301:100Hanyu, T, et al. 2018. Expression of phosphorylated sphingosine kinase 1 is associated with diffuse type and lymphatic invasion in human gastric cancer. Surgery, 1301-1306.
278643311:200Fu, P, et al. 2016. Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium. The journal of biological chemistry, 27187-27203.
Immunohistochemistry: Mouse
PMID Dilution Publication
29523764not listedYamada, A, et al. 2018. ABCC1-Exported Sphingosine-1-phosphate, Produced by Sphingosine Kinase 1, Shortens Survival of Mice and Patients with Breast Cancer. Molecular cancer research : MCR, 1059-1070.
Immunohistochemistry: Rat
PMID Dilution Publication
31371480not listedAlganga, H, et al. 2019. Short Periods of Hypoxia Upregulate Sphingosine Kinase 1 and Increase Vasodilation of Arteries to Sphingosine 1-Phosphate (S1P) via S1P3. The journal of pharmacology and experimental therapeutics, 63-74.
Western Blot: Human
PMID Dilution Publication
38287231not listedPrisinzano, M., et al. 2024. Sphingosine 1-phosphate signaling axis mediates neuropeptide S-induced invasive phenotype of endometriotic cells. The FEBS Journal, .
37830619not listedEpshtein, Y, et al. 2023. UCHL1 Regulates Radiation Lung Injury via Sphingosine Kinase-1. Cells, 2504.
375821601:1000Bergkamp, ND, et al. 2023. A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis. Science Signaling, eade6737.
36358599not listedHengst, JA, et al. 2022. Regulatory Role of Sphingosine-1-Phosphate and C16:0 Ceramide, in Immunogenic Cell Death of Colon Cancer Cells Induced by Bak/Bax-Activation. Cancers, 5182.
35159039not listedPetrusca, DN, et al. 2022. GFI1-Dependent Repression of SGPP1 Increases Multiple Myeloma Cell Survival. Cancers, 772.
33931106not listedDai, L, et al. 2021. Activation of SphK1 by adipocytes mediates epithelial ovarian cancer cell proliferation. Journal of ovarian research, 62.
33525436not listedBernacchioni, C, et al. 2021. Role of Sphingosine 1-Phosphate Signalling Axis in Muscle Atrophy Induced by TNFα in C2C12 Myotubes. International journal of molecular sciences, 1280.
31413745not listedWu, X, et al. 2019. SphK1 functions downstream of IGF-1 to modulate IGF-1-induced EMT, migration and paclitaxel resistance of A549 cells: A preliminary in vitro study. Journal of cancer, 4264-4269.
313630401:1000Kao, LP, et al. 2019. Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells. Journal of lipid research, 1590-1602.
30118478not listedArish, M, et al. 2018. Sphingosine-1-phosphate signaling in Leishmania donovani infection in macrophages. PLoS neglected tropical diseases, e0006647.
294275281:500Cattaneo, MG, et al. 2018. Cross-talk between sphingosine-1-phosphate and EGFR signaling pathways enhances human glioblastoma cell invasiveness. FEBS letters, 949-961.
282403501:1000Lee, HM, et al. 2017. Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3. The journal of pathology, 62-72.
27956387not listedPowell, J, et al. 2017. Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia. Blood, 771-782.
27864331not listedFu, P, et al. 2016. Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium. The journal of biological chemistry, 27187-27203.
24137500not listedSeo, YJ, et al. 2013. Sphingosine kinase 1 serves as a pro-viral factor by regulating viral RNA synthesis and nuclear export of viral ribonucleoprotein complex upon influenza virus infection. PLoS One, e75005.
20634980not listedBenakanakere, MR, et al. 2010. Sphingosine kinase-1 is required for toll mediated beta-defensin 2 induction in human oral keratinocytes. PLoS One, e11512.
18426913not listedMiller, AV, et al. 2008. Sphingosine kinases and sphingosine-1-phosphate are critical for transforming growth factor beta-induced extracellular signal-regulated kinase 1 and 2 activation and promotion of migration and invasion of esophageal cancer cells. Molecular and cellular biology, 4142-4151.
Western Blot: Mouse
PMID Dilution Publication
37392305not listedTan ,J, et al. 2023. Ritanserin suppresses acute myeloid leukemia by inhibiting DGKα to downregulate phospholipase D and the Jak-Stat/MAPK pathway. Discover. Oncology, 118.
35203362not listedBernacchioni, C, et al. 2022. S1P Signalling Axis Is Necessary for Adiponectin-Directed Regulation of Electrophysiological Properties and Oxidative Metabolism in C2C12 Myotubes. Cells, 713.
32771459not listedRanasinghe, ADCU, et al. 2020. Mechanistic regulation of SPHK1 expression and translocation by EMAP II in pulmonary smooth muscle cells. Biochimica et biophysica acta. Molecular and cell biology of lipids, 158789.
31971297not listedMohammed, S, et al. 2020. Regulatory role of SphK1 in TLR7/9-dependent type I interferon response and autoimmunity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 4329-4347.
30569280not listedGrassi, S, et al. 2019. Human Remyelination Promoting Antibody Stimulates Astrocytes Proliferation Through Modulation of the Sphingolipid Rheostat in Primary Rat Mixed Glial Cultures. Neurochemical research, 1460-1474.
302791381:1000Pierucci, F, et al. 2018. Involvement of released sphingosine 1-phosphate/sphingosine 1-phosphate receptor axis in skeletal muscle atrophy. Biochimica et biophysica acta. Molecular basis of disease, 3598-3614.
288909351:1000Hengst, J, et al. 2017. SKI-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models. Cancer translational medicine, 109-121.
274851221:500Salta, E, et al. 2016. miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain. EMBO molecular medicine, 1005-1018.
24464131not listedHarikumar, KB, et al. 2014. K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5. Nature immunology, 231-238.
Additional Publications: Unspecified
PMID Publication
37225163Medina-Moctezuma, ZB, et al. 2023. Sphingosine-1-phosphate Regulation of Luteinising Hormone-induced Steroidogenesis and Proliferation of Bovine Theca Cells in Vitro. Reproduction, Fertility, and Development, 518-526.

Bulk Order Anti-Sphingosine Kinase 1 (Ser-225), Phosphospecific Antibody

Related Products

Recently Viewed