Western blot of rat kidney lysate showing specific immunolabeling of the ~21 kDa Park7 protein.
Anti-Park7 (DJ-1) Antibody
Bulk Order Anti-Park7 (DJ-1) Antibody
Park7, also known as DJ-1, is a member of the peptidase C56 family of proteins and is thought to function as a molecular chaperone. Mutations in park7 have been associated with autosomal recessive, early onset Parkinson’s disease (Bonifati et al., 2003). Recently, park7 has been shown to inhibit microtubule associated protein 1B aggregation thus leading to neuronal apoptosis (Wang et al., 2011).
Protein G purified culture supernatant
ICC, IHC, WB
Full length recombinant human Park7 expressed in and purified from E. coli.
Bovine, Human, Mouse, Rat
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
Protein G purified culture supernatant.
PBS + 10 mM NaN3.
Specific for endogenous levels of the ~21 kDa Park7 protein.
Western blots performed on each lot.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
After date of receipt, stable for at least 1 year at -20°C.
CAP1 antibody, DJ-1 antibody, DJ1 antibody, DJ1 protein antibody, Epididymis secretory sperm binding protein Li 67p antibody, FLJ27376 antibody, FLJ34360 antibody, FLJ92274 antibody, HEL S 67p antibody, Oncogene DJ1 antibody, OTTHUMP00000001348 antibody, OTTHUMP00000001349 antibody, OTTHUMP00000001350 antibody, OTTHUMP00000001351 antibody, PARK7 antibody, PARK7_HUMAN antibody, Parkinson disease (autosomal recessive, early onset) 7 antibody, Parkinson disease protein 7 antibody, Parkinson protein 7 antibody, Protein DJ-1 antibody, SP22 antibody
Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ , Krieger E, Dekker MC, Squitieri F, Ibanez P, Joosse M, van Dongen JW, Vanacore N, van Swieten JC, Brice A, Meco G, van Duijn CM, Oostra BA, Heutink P. (2003) Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science. Jan 10;299(5604):256-9. PMID: 12446870
Wang Z, Zhang Y, Zhang S, Guo Q, Tan Y, Wang X, Xiong R, Ding J, Chen S. (2011) DJ-1 can inhibit microtubule associated protein 1 B formed aggregates. Mol Neurodegener. Jun 6;6:38. PMID: 21645326
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