Anti-P-Zero Myelin Protein Antibody

Two antipeptide antibodies were generated in chickens against sequences shared between the mouse (NP_032649) and human (NP_000521) gene products. Antibodies were affinity-purified and mixed in equal concentrations. These antibodies have been validated with human, mouse and rat tissues.



SKU: PZO

Volume: 1000 µL
Price:
Sale price$455

Product Specific References for Applications and Species

Immunocytochemistry: Human
PMID Dilution Publication
285126491:500Stratton, J.A., et al. 2017. Purification and Characterization of Schwann Cells from Adult Human Skin and Nerve. eNeuro, .
Immunocytochemistry: Mouse
PMID Dilution Publication
376426481:500Mutschler, C, et al. 2023. Schwann cells are axo-protective after injury irrespective of myelination status in mouse Schwann cell-neuron cocultures. Journal of Cell Science, .
371276731:1000Govindappa, P.K., et al. 2023. A critical role for erythropoietin on vagus nerve Schwann cells in intestinal motility. BMC Biotechnology, 12.
352966511:1000Govindappa, P.K., et al. 2022. Erythropoietin promotes M2 macrophage phagocytosis of Schwann cells in peripheral nerve injury. Cell death & disease, 245.
342881201:500Booth, D.G., et al. 2021. Characterizing the molecular etiology of arthrogryposis multiplex congenita in patients with LGI4 mutations. Glia, 2605-2617.
299769261:500Volpi, V.G., et al. 2018. Zika Virus Replication in Dorsal Root Ganglia Explants from Interferon Receptor1 Knockout Mice Causes Myelin Degeneration. Scientific Reports, 10166.
297785231:250Park, J., et al. 2018. Local Immunomodulation with Anti-inflammatory Cytokine-Encoding Lentivirus Enhances Functional Recovery after Spinal Cord . Molecular Therapy, 1756-1770.
Immunocytochemistry: Rat
PMID Dilution Publication
362229461:1000Suzuki, T., et al. 2022. Molecular and Regenerative Characterization of Repair and Non-repair Schwann Cells. Cellular and Molecular Neurobiology, .
Immunohistochemistry: Human
PMID Dilution Publication
285126491:500Stratton, J.A., et al. 2017. Purification and Characterization of Schwann Cells from Adult Human Skin and Nerve. eNeuro, .
Immunohistochemistry: Mouse
PMID Dilution Publication
377680191:250Ross, BC, et al. 2023. Building-Block Size Mediates Microporous Annealed Particle Hydrogel Tube Microenvironment Following Spinal Cord Injury. Advanced healthcare materials, e2302498.
36479906not listedProcacci, N.M., et al. 2022. Kir4.1 is Specifically Expressed and Active in Non-myelinating Schwann Cells. Glia, .
363508841:300Shackleford, G., et al. 2022. A New Mouse Model Of Charcot-Marie-Tooth 2J Neuropathy Replicates Human Axonopathy And Suggest Alteration In Axo-Glia Communication. PLoS Genetics, e1010477.
363508841:300Shackleford, G., et al. 2022. A New Mouse Model Of Charcot-Marie-Tooth 2J Neuropathy Replicates Human Axonopathy And Suggest Alteration In Axo-Glia Communication. PLoS Genetics, e1010477.
36307805not listedManto, K.M., et al. 2022. Erythropoietin-PLGA-PEG as a Local Treatment to Promote Functional Recovery and Neurovascular Regeneration After Peripheral Nerve Injury. Journal of Nanobiotechnology, 461.
342407061:200Malavasi, E.L., et al. 2021. Dynamic early clusters of nodal proteins contribute to node of Ranvier assembly during myelination of peripheral neurons. eLife, e68089.
337283921:200Ehsanipour, A., et al. 2021. Injectable, macroporous scaffolds for delivery of therapeutic genes to the injured spinal cord. APL Bioengineering, 16104.
335387621:1000Wang, M., et al. 2021. Completion of neuronal remodeling prompts myelination along developing motor axon branches. Cellular Neurobiology, .
335084301:250Heller, G.J., et al. 2021. Waning efficacy in a long-term AAV-mediated gene therapy study in the murine model of Krabbe disease. Molecular Therapy, 1883-1902.
334995081:500Lee, J.I., et al. 2021. Purposeful Misalignment of Severed Nerve Stumps in a Standardized Transection Model Reveals Persistent Functional Deficit With Aberrant Neurofilament Distribution. Military Medicine, 696-703.
333037981:500Lee, J.I., et al. 2020. A novel nerve transection and repair method in mice: histomorphometric analysis of nerves, blood vessels, and muscles with functional recovery. Scientific Reports, 21637.
328079501:1000Babetto, E., et al. 2020. A glycolytic shift in Schwann cells supports injured axons. Nature Neuroscience, 1215-1228.
326728151:500Wüst, H.M., et al. 2020. Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination. Nucleic Acids Research, 8959-8976.
326414021:800Reed, C.B., et al. 2020. Deletion of Calcineurin in Schwann Cells Does Not Affect Developmental Myelination, But Reduces Autophagy and Delays Myelin Clearance after Peripheral Nerve Injury. Journal of Neuroscience, 6165-6176.
32375064not listedWeinstock, N.I., et al. 2020. Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction. Neuron, 65-81.
32209430not listedEshed-Eisenbach, Y., et al. 2020. Precise Spatiotemporal Control of Nodal Na+ Channel Clustering by Bone Morphogenetic Protein1/Tolloid-like Proteinases. Neuron, 806-815.
321430011:1000Govindappa, P.K., et al. 2020. An effective erythropoietin dose regimen protects against severe nerve injury-induced pathophysiological changes with improved neural gene expression and enhances functional recovery. International Immunopharmacology, 106330.
32000627not listedSmith, D.R., et al. 2020. Polycistronic Delivery of IL-10 and NT-3 Promotes Oligodendrocyte Myelination and Functional Recovery in a Mouse Spinal Cord Injury Model. Tissue Engineering, 672-682.
33423486not listedSmith, D.R., et al. 2019. PLG bridge implantation in chronic SCI promotes axonal elongation and myelination. ACS Biomaterials Science & Engineering, 6679-6690.
312853391:250Park, J., et al. 2019. Intravascular innate immune cells reprogrammed via intravenous nanoparticles to promote functional recovery after spinal cord injury. PNAS: USA, 14947-14954.
30901424not listedNoble, M., et al. 2019. 4-Aminopyridine as a Single Agent Diagnostic and Treatment for Severe Nerve Crush Injury. Military Medicine, 379-385.
306109181:250Dumont, C.M., et al. 2018. Aligned hydrogel tubes guide regeneration following spinal cord injury. Acta Biomaterialia, 312-322.
305353601:1000Belin, S., et al. 2018. Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of Congenital Hypomyelinating Neuropathy. Human Molecular Genetics, 1260-1273.
30229864not listedSmith, D.R., et al. 2018. Combinatorial lentiviral gene delivery of pro‐oligodendrogenic factors to improve myelination of regenerating axons after spinal cord injury. Biotechnology and Bioengineering, 155-167.
301844911:200Stratton, J.A., et al. 2018. Macrophages Regulate Schwann Cell Maturation after Nerve Injury. Cell Reports, 2561-2572.
293610541:2000Truch, K., et al. 2018. Analysis of the human SOX10 mutation Q377X in mice and its implications for genotype-phenotype correlation in SOX10-related human disease.. Human Molecular Genetics, 1078-1092.
287608621:100Assinck, P., et al. 2017. Myelinogenic Plasticity of Oligodendrocyte Precursor Cells following Spinal Cord Contusion Injury. The Journal of Neuroscience, 8635-8654.
281687031:1000Geary, M.B., et al. 2016. Erythropoietin accelerates functional recovery after moderate sciatic nerve crush injury. Muscle & Nerve, 143-151.
281396831:500Brügger, V., et al. 2016. Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration. Nature Communications, 14272.
275934861:1000Sundem, L., et al. 2016. Erythropoietin Enhanced Recovery After Traumatic Nerve Injury: Myelination and Localized Effects. The Journal of Hand Surgery, 999-1010.
Immunohistochemistry: Rat
PMID Dilution Publication
35434551not listedPark, H., et al. 2022. ACTL6a coordinates axonal caliber recognition and myelination in the peripheral nerve.. iScience, 104132.
345196411:300Nunes, G.D.F., et al. 2021. Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination. Elife, e66278.
325594591:100Assinck, P., et al. 2020. Transplantation of Skin Precursor-Derived Schwann Cells Yields Better Locomotor Outcomes and Reduces Bladder Pathology in Rats with Chronic Spinal Cord Injury. Stem Cell Reports, 140-155.
305110191:100Estrada, V., et al. 2018. Low-pressure micro-mechanical re-adaptation device sustainably and effectively improves locomotor recovery from complete spinal cord injury. Nature Communications Biology, 205.
301844911:200Stratton, J.A., et al. 2018. Macrophages Regulate Schwann Cell Maturation after Nerve Injury. Cell Reports, 2561-2572.
278899271:500Wegener, A., et al. 2016. Sp2 is the only glutamine-rich Specificity protein with minor impact on development and differentiation in myelinating glia. Journal of Neurochemistry, 245-256.
261214891:200Stratton, J.A., et al. 2015. The immunomodulatory properties of adult skin-derived precursor Schwann cells: implications for peripheral nerve injury therapy. European Journal of Neuroscience, 365-375.
273438031:1000Sapio, M.R., et al. 2009. Transcriptomic analyses of genes and tissues in inherited sensory neuropathies. Experimental Neurology, 375-395.
Immunohistochemistry: Swine
PMID Dilution Publication
338625961:1000Hellman, A., et al. 2021. Development of a common peroneal nerve injury model in domestic swine for the study of translational neuropathic pain treatments. Journal of Neurosurgery, 1-8.
Immunoprecipitation: Mouse
PMID Dilution Publication
29076578not listedVerPlank, J.J.S., et al. 2018. Impairment of protein degradation and proteasome function in hereditary neuropathies. Glia, 379-395.
Western Blot: Mouse
PMID Dilution Publication
363508841:5000Shackleford, G., et al. 2022. A New Mouse Model Of Charcot-Marie-Tooth 2J Neuropathy Replicates Human Axonopathy And Suggest Alteration In Axo-Glia Communication. PLoS Genetics, e1010477.
333368551:5000Jeanette, H., et al. 2020. YAP and TAZ regulate Schwann cell proliferation and differentiation during peripheral nerve regeneration. Glia, 1061-1074.
326414021:1000Reed, C.B., et al. 2020. Deletion of Calcineurin in Schwann Cells Does Not Affect Developmental Myelination, But Reduces Autophagy and Delays Myelin Clearance after Peripheral Nerve Injury. Journal of Neuroscience, 6165-6176.
314536491:4000Jha, M.K., et al. 2020. Monocarboxylate transporter 1 in Schwann cells contributes to maintenance of sensory nerve myelination during aging. Glia, 161-177.
30901424not listedNoble, M., et al. 2019. 4-Aminopyridine as a Single Agent Diagnostic and Treatment for Severe Nerve Crush Injury. Military Medicine, 379-385.
305353601:5000Belin, S., et al. 2018. Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of Congenital Hypomyelinating Neuropathy. Human Molecular Genetics, 1260-1273.
29076578not listedVerPlank, J.J.S., et al. 2018. Impairment of protein degradation and proteasome function in hereditary neuropathies. Glia, 379-395.
291092391:2000Fazal, S.V., et al. 2017. Graded Elevation of c-Jun in Schwann Cells In Vivo: Gene Dosage Determines Effects on Development, Remyelination, Tumorigenesis, and Hypomyelination. Journal of Neuroscience, 12297-12313.
28484008not listedBeirowski,B., et al. 2017. mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells. PNAS: USA, E4261-E4270.
281396831:1000Brügger, V., et al. 2016. Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration. Nature Communications, 14272.
Western Blot: Rat
PMID Dilution Publication
25762662not listedDomenech-Estevez, E., et al. 2015. Distribution of Monocarboxylate Transporters in the Peripheral Nervous System Suggests Putative Roles in Lactate Shuttling and Myelination. The Journal of Neuroscience, 4151-4156.
Additional Publications: Unspecified
PMID Publication
31479164Forese, M.G., et al. 2020. Prostaglandin D2 synthase modulates macrophage activity and accumulation in injured peripheral nerves. Glia, 95-110.

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