Anti-Nurr1 Antibody

Name: Anti-Nurr1 Antibody
Brand: PhosphoSolutions
SKU: 24523
Price: 415.0 USD
Availability: InStock

from PhosphoSolutions

Our Nurr1 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat Nurr1 and is antigen affinity purified. It is great for use in WB.

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Applications

Host Species

Rabbit

Format

Antigen Affinity Purified

Gene Name

NR4A2

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Western Blot of 20 ug of human hippocampus tissue lysate (lanes 2 and 4) showing specific immunolabeling of Nurr1. Peptide absorption control lane 3.

Immunohistochemistry of adult rat brain hippocampus showing specific staining of Nurr1. Tissue was fixed in paraformaldehyde and cut into 20 micron sections.

Title: 100 µL

Variant

Price:

$415

Quantity:

Bulk Order Anti-Nurr1 Antibody

Product Details

Target

Nurr1

Target Description

The Nurr1 gene encodes a member of the steroid-thyroid hormone- retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's. Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of murine and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype. In addition, Nurr1 is involved in the regulation of corticotropin-releasing hormone (CRH), which may be linked to and associated with rheumatoid arthritis.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

Host Species

Rabbit

Gene Name

NR4A2

Antigen

Synthetic peptide corresponding to amino acids from an internal sequence of the human Nurr1 protein

Species Reactivity

Human, Mouse, Rat

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with an internal sequence of the human Nurr1 protein. Also reacts with rat and mouse Nurr1.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

NR4A2, Nuclear receptor subfamily 4 group A member 2, Immediate-early response protein NOT, Orphan nuclear receptor NURR1, Transcriptionally-inducible nuclear receptor, NOT, NURR1, TINUR

UniProt Details

UniProt (Human): P43354
UniProt (Immunogen Species): P43354

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Anti-Nurr1 Antibody

Our Nurr1 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat Nurr1 and is antigen affinity purified. It is great for use in WB.