Anti-Neuropilin-2 (MAM Domain) Antibody (M391)

Name: Anti-Neuropilin-2 (MAM Domain) Antibody
Brand: PhosphoSolutions
SKU: NM3911
Price: 255.0 USD
Availability: InStock

from PhosphoSolutions

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

M391

Applications

Host Species

Mouse

Format

Protein A Purified

Gene Name

NRP2

Molecular Weight

130

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Western blot analysis of neuropilin-2 (NRP-2) expression in neonatal rat brain. The blot was probed with mouse monoclonal anti-NRP-2 (MAM Domain) at 1:250.

Volume: 100 µL

Variant

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$255

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Product Details

Target

Neuropilin-2 (MAM Domain)

Target Description

Neuropilins are transmembrane proteins that contain two CUB domains (a1 and a2), two coagulation factor-like domains (b1 and b2), and a MAM domain in the extracellular region. These proteins have short cytoplasmic domains that include a PDZ-binding motif. The neuropilin (NRP) family includes NRP-1, NRP-2A, and NRP-2B. NRP-1 and NRP-2 can form a heterodimer. NRP-1 binds with high affinity to Semaphorin 3A, while NRP-2 binds with high affinity to Semaphorin 3F. Both NRP-1 and NRP-2 have been implicated in VEGFR and Plexin receptor function, and both neuropilins may be involved in axon guidance, angiogenesis, and tumor progression

Format

Protein A Purified

Clonality

Monoclonal

Clone

M391

Isotype

IgG1

Applications

Host Species

Mouse

Gene Name

NRP2

Molecular Weight

130

Antigen

Clone M391 was generated from Neuropilin-2 recombinant protein containing amino acids in the MAM domain region of rat neuropilin-2. This sequence is highly conserved in human and mouse neuropilin-2, and has low homology to neuropilin-1.

Species Reactivity

Human, Mouse, Rat

Storage

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Physical State

Liquid

Buffer

PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol

Dilution Ranges

WB: 1:500

Conjugate

Unconjugated

Specificity

This antibody detects a 130 kDa* protein corresponding to the apparent molecular mass of neuropilin-2 on SDS-PAGE immunoblots of rat brain.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

NRP2, VEGF receptor 165, VEGFR

UniProt Details

UniProt (Human): O60462
UniProt (Immunogen Species): O35276

Product Specific Protocols

Western Blot Protocol: Download

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Anti-Neuropilin-2 (MAM Domain) Antibody (M391)

Anti-Neuropilin-2 (MAM Domain) Antibody
SKU: NM3911

Bulk Order Anti-Neuropilin-2 (MAM Domain) Antibody

Product Details

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Anti-Neuropilin-2 (MAM Domain) Antibody (M391)

Anti-Neuropilin-2 (MAM Domain) Antibody SKU: NM3911

Bulk Order Anti-Neuropilin-2 (MAM Domain) Antibody

Product Details

Product Specific Protocols

Anti-Neuropilin-2 (MAM Domain) Antibody
SKU: NM3911