The novel LRRK2 gene (also known as PARK8), is responsible for up to 6% of all autosomal dominant Parkinson’s disease (PD). LRRK2 missense mutations segregate with PARK8-linked PD and are implicated in other neurodegenerative diseases involving alpha-synuclein and tau pathology.
Antigen Affinity Purified
Synthetic peptide corresponding to amino acids from the C-terminal region of the human LRRK2 protein.
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
PBS + 0.02% NaN3
WB Brain: 1:500-1:1000
Reacts with the C-terminal region of the 260 kDa human LRRK2 protein. 88% sequence identity in mouse and rat.
Western blots performed on each lot.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
After date of receipt, stable for at least 1 year at -20°C.