Anti-Kv2.1 K+ Channel Antibody (K89/34)
Primary Antibody
Human, Mouse, Rat
K89/34
IHC, IP, WB
Mouse
Purified
Kcnb1
105-125 kDa (varies with cell background due to phosphorylation)
![Immunoblots on brain membranes prepared from whole rat (RBM) and mouse (MBM) brain, and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] and cerebellum [HBM(Cb)].](http://cdn.shopify.com/s/files/1/0520/9063/4413/products/validation-image-73-014-k89-34-wb-3_{width}x.jpg?v=1626903310)
Adult rat hippocampus immunohistochemistry.
![Immunoblots on brain membranes prepared from whole rat (RBM) and mouse (MBM) brain, and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] and cerebellum [HBM(Cb)].](http://cdn.shopify.com/s/files/1/0520/9063/4413/products/validation-image-73-014-k89-34-wb-3_1024x.jpg?v=1626903310)
Product Specific References for Applications and Species
- Electrophysiology: Rat
- Immunocytochemistry: Hamster | Human | Mouse | Rat
- Immunohistochemistry: Hamster | Human | Mouse | Non-Human Primate | Rat
- Immunoprecipitation: Mouse
- SDS-FRL: Mouse | Rat
- Western Blot: Hamster | Human | Mouse | Rat
- Additional Publications: Unspecified
| Electrophysiology: Rat | ||
| PMID | Dilution | Publication |
| 33854181 | 0.5 µg/mL | Dallas, M.L., et al. 2021. Hydrogen sulfide regulates hippocampal neuron excitability via S-sulfhydration of Kv2. 1. Scientific Reports, 8194. |
| Immunocytochemistry: Hamster | ||
| PMID | Dilution | Publication |
| 31682765 | not listed | Yu, W., et al. 2019. Complexes formed with integrin-α5 and KCNB1 potassium channel wild type or epilepsy-susceptibility variants modulate cellular plasticity via Ras and Akt signaling. The FASEB Journal, 14680-9. |
| Immunocytochemistry: Human | ||
| PMID | Dilution | Publication |
| 30091655 | 1:5 (supe) | Kirmiz, M., et al. 2018. Remodeling neuronal ER–PM junctions is a conserved nonconducting function of Kv2 plasma membrane ion channels. Molecular Neurobiology of the Cell, 2410-32. |
| 26503721 | not listed | Thiffault, I., et al. 2015. A novel epileptic encephalopathy mutation in KCNB1 disrupts Kv2.1 ion selectivity, expression, and localization.. The Journal of General Physiology, 399-410. |
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 34435615 | 10 µg/mL | Newkirk, G.S., et al. 2022. Kv2. 1 potassium channels regulate repetitive burst firing in extratelencephalic neocortical pyramidal neurons. Cerebral Cortex, 1055-76. |
| 34280489 | 1:500 | Ding, T., et al. 2021. Kv2.1 expression in giant reticular neurons of the postnatal mouse brain. Journal of Chemical Neuroanatomy, 102005. |
| 31600826 | 1:2 (supe) | Kang, S.K., et al. 2019. Spectrum of KV2.1 Dysfunction in KCNB1‐Associated Neurodevelopmental Disorders. Annals of Neurology, 899-912. |
| 28065942 | 1:100 | Casanovas, A., et al. 2017. Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury. Scientific Reports, 40155. |
| 20853508 | not listed | Hermanstyne, T.O., et al. 2010. Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice.. Journal of Comparative Neurology, 4298-310. |
| Immunocytochemistry: Rat | ||
| PMID | Dilution | Publication |
| 31594866 | 10 µg/mL | Kirmiz, M., et al. 2019. Neuronal ER–plasma membrane junctions organized by Kv2–VAP pairing recruit Nir proteins and affect phosphoinositide homeostasis. Journal of Biological Chemistry, 17735-57. |
| 30667360 | 1:10 (supe) | Andrews, N.P., et al. 2019. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain. eLife, e43322. |
| 29395909 | not listed | Berger, S.L., et al. 2018. Localized Myosin II Activity Regulates Assembly and Plasticity of the Axon Initial Segment. Neuron, 555-570. |
| 26442584 | not listed | Cobb, M.M., et al. 2015. Cell Cycle-dependent Changes in Localization and Phosphorylation of the Plasma Membrane Kv2.1 K+ Channel Impact Endoplasmic Reticulum Membrane Contact Sites in COS-1 Cells.. The Journal of Biological Chemistry, 29189-201. |
| 20853508 | not listed | Hermanstyne, T.O., et al. 2010. Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice.. Journal of Comparative Neurology, 4298-310. |
| Immunohistochemistry: Hamster | ||
| PMID | Dilution | Publication |
| 31591393 | not listed | Yu, W., et al. 2017. Oxidation of KCNB1 potassium channels triggers apoptotic integrin signaling in the brain. Cell Death & Disease, e2737. |
| 28383553 | not listed | Yu, W., et al. 2017. Oxidation of KCNB1 potassium channels triggers apoptotic integrin signaling in the brain. Cell Death & Disease, e2737. |
| Immunohistochemistry: Human | ||
| PMID | Dilution | Publication |
| 29483285 | 1:800 | Gayet-Primo, J., et al. 2018. Heteromeric KV2/KV8. 2 channels mediate delayed rectifier potassium currents in primate photoreceptors. Journal of Neuroscience, 3414-27. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 36640913 | 1:500 | Otuyemi, B., et al. 2023. Domain and Cell Type-specific Immunolocalisation of Voltage-gated Potassium Channels in the Mouse Striatum. Journal of Chemical Neuroanatomy, 102233. |
| 36130488 | not listed | Cserép, C., et al. 2022. Microglial Control of Neuronal Development via Somatic Purinergic Junctions. Cell Reports, 111369. |
| 35201268 | 1:500 | Császár, E., et al. 2022. Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions. The Journal of experimental medicine, . |
| 34652420 | 1:1500 | Inamdar, S.M., et al. 2022. Differential impact of Kv8. 2 loss on rod and cone signaling and degeneration. Human Molecular Genetics, 1035-50. |
| 34825141 | not listed | Buettner, J.M., et al. 2021. Central synaptopathy is the most conserved feature of motor circuit pathology across spinal muscular atrophy mouse models. iScience, 103376. |
| 33333928 | not listed | Song, M.Y., et al. 2020. Tyrosine Phosphorylation of the Kv2. 1 Channel Contributes to Injury in Brain Ischemia. International Journal of Molecular Sciences, 9538. |
| 32937450 | 1:200 | Schulien, A.J., et al. 2020. Targeted disruption of Kv2.1-VAPA association provides neuroprotection against ischeemic stroke in mice by declustering Kv2.1 channels. Science Advances, eaaz8110. |
| 32684634 | 1:1000 | Asede, D., et al. 2020. Deletion of NRXN1α impairs long-range and local connectivity in amygdala fear circuit. Translational Pyschiatry, 242. |
| 31987008 | 1:500 | Varga, D.P., et al. 2020. Microglia alter the threshold of spreading depolarization and related potassium uptake in the mouse brain. Journal of Cerebral Blood Flow and Metabolism, S67-80. |
| 31831638 | not listed | Cserép, C., et al. 2020. Microglia monitor and protect neuronal function through specialized somatic purinergic junctions. Science, 528-537. |
| 31664163 | 1:1000 | Thiebaud, N., et al. 2019. A unique olfactory bulb microcircuit driven by neurons expressing the precursor to glucagon-like peptide 1. Scientific Reports, 15542. |
| 31345270 | 1:100 | Nishino, K., et al. 2019. Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1−Akt signaling pathway. Acta Neuropathologica Communications, 118. |
| 30912977 | 1:100 | Salvany, S., et al. 2019. Localization and dynamic changes of neuregulin-1 at C-type synaptic boutons in association with motor neuron injury and repair. The FASEB Journal, 7833-51. |
| 30050035 | not listed | Wei, Y., et al. 2018. Oxidation of KCNB1 channels in the human brain and in mouse model of Alzheimer’s disease. Cell Death & Disease, 820. |
| 30012696 | 1:10 (supe) | Kirmiz, M., et al. 2018. Identification of VAPA and VAPB as Kv2 Channel-Interacting Proteins Defining Endoplasmic Reticulum–Plasma Membrane Junctions in Mammalian Brain Neurons. The Journal of Neuroscience, 7562-84. |
| 29954847 | 1:1000 | Rhomberg, T., et al. 2018. Vasoactive Intestinal Polypeptide-Immunoreactive Interneurons within Circuits of the Mouse Basolateral Amygdala. The Journal of Neuroscience, 6983-7003. |
| 29502344 | 1:1000 | Dukkipati, S.S., et al. 2018. The vulnerability of spinal motoneurons and soma size plasticity in a mouse model of amyotrophic lateral sclerosis. The Journal of Physiology, 1723-45. |
| 29403353 | not listed | Bishop, H.I., et al. 2018. Kv2 Ion Channels Determine the Expression and Localization of the Associated AMIGO-1 Cell Adhesion Molecule in Adult Brain Neurons.. Frontiers in Molecular Neuroscience, 1. |
| 28856240 | 5 µg/mL | Palacio, S., et al. 2017. Heterogeneity in Kv2 Channel Expression Shapes Action Potential Characteristics and Firing Patterns in CA1 versus CA2 Hippocampal Pyramidal Neurons. eNeuro, ENEURO.0267-17.2017. |
| 28060701 | 1:1000 | Veres, J.M., et al. 2017. Perisomatic GABAergic synapses of basket cells effectively control principal neuron activity in amygdala networks. eLife, e20721. |
| 27798188 | 1:100 | Yu, W., et al. 2016. Oxidation of KCNB1 Potassium Channels Causes Neurotoxicity and Cognitive Impairment in a Mouse Model of Traumatic Brain Injury.. Journal of Neuroscience, 11084-11096. |
| 26891847 | 1:250 | Lasiene, J., et al. 2016. Neuregulin 1 confers neuroprotection in SOD1-linked amyotrophic lateral sclerosis mice via restoration of C-boutons of spinal motor neurons.. Acta Neuropathologica Communications, 15. |
| 24962901 | 1:100 | Mandikian, D., et al. 2014. Cell type-specific spatial and functional coupling between mammalian brain Kv2.1 K+ channels and ryanodine receptors.. Journal of Comparative Neurology, 3555-74. |
| 24494598 | not listed | Speca, D.J., et al. 2014. Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability.. Genes, Brain and Behavior, 394-408. |
| 20853508 | not listed | Hermanstyne, T.O., et al. 2010. Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice.. Journal of Comparative Neurology, 4298-310. |
| Immunohistochemistry: Non-Human Primate | ||
| PMID | Dilution | Publication |
| 34716617 | 1:300 | Muñoz, Y., et al. 2021. Light microscopic and heterogeneity analysis of astrocytes in the common marmoset brain.. Journal of Neuroscience Research, 3121-3147. |
| Immunohistochemistry: Rat | ||
| PMID | Dilution | Publication |
| 33333928 | not listed | Song, M.Y., et al. 2020. Tyrosine Phosphorylation of the Kv2. 1 Channel Contributes to Injury in Brain Ischemia. International Journal of Molecular Sciences, 9538. |
| 32726631 | not listed | Holderith, N., et al. 2020. A High-Resolution Method for Quantitative Molecular Analysis of Functionally Characterized Individual Synapses. Cell Reports, 107968. |
| 31594866 | 10 µg/mL | Kirmiz, M., et al. 2019. Neuronal ER–plasma membrane junctions organized by Kv2–VAP pairing recruit Nir proteins and affect phosphoinositide homeostasis. Journal of Biological Chemistry, 17735-57. |
| 24723263 | 1:250 | Dufour, M.A., et al. 2014. Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development.. Journal of Neuroscience Research, 981-99. |
| 22675541 | not listed | Manning, C.F., et al. 2012. Benefits and pitfalls of secondary antibodies: why choosing the right secondary is of primary importance.. PLoS One, e38313. |
| 20853508 | not listed | Hermanstyne, T.O., et al. 2010. Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice.. Journal of Comparative Neurology, 4298-310. |
| Immunoprecipitation: Mouse | ||
| PMID | Dilution | Publication |
| 30922570 | 10 µg | Yu, W., et al. 2019. Oxidation of KCNB1 potassium channels in the murine brain during aging is associated with cognitive impairment. Biochemical and Biophysical Research Communications, 665-9. |
| SDS-digested freeze fracture replica-labeling: Mouse | ||
| PMID | Dilution | Publication |
| 29127366 | 1:100 | Szoboszlay, M., et al. 2017. Objective quantification of nanoscale protein distributions. Scientific Reports, 15240. |
| SDS-digested freeze fracture replica-labeling: Rat | ||
| PMID | Dilution | Publication |
| 29127366 | 1:100 | Szoboszlay, M., et al. 2017. Objective quantification of nanoscale protein distributions. Scientific Reports, 15240. |
| Western Blot: Hamster | ||
| PMID | Dilution | Publication |
| 29264390 | 1:250 | Calhoun, J.D., et al. 2017. Characterization of a KCNB1 variant associated with autism, intellectual disability, and epilepsy. Neurology Genetics, e198. |
| Western Blot: Human | ||
| PMID | Dilution | Publication |
| 34137443 | 1:1000 | Maverick, E.E., et al. 2021. Kv2 channel–AMIGO β-subunit assembly modulates both channel function and cell adhesion molecule surface trafficking. Journal of Cell Science, jcs256339. |
| 32284408 | not listed | Möller, L., et al. 2020. Determining the correct stoichiometry of Kv2.1/Kv6.4 heterotetramers, functional in multiple stoichiometrical configurations. PNAS, 9365-76. |
| 29483285 | 1:800 | Gayet-Primo, J., et al. 2018. Heteromeric KV2/KV8. 2 channels mediate delayed rectifier potassium currents in primate photoreceptors. Journal of Neuroscience, 3414-27. |
| 28938641 | 1:1000 | Liu, X., et al. 2017. Potential independent action of sigma receptor ligands through inhibition of the Kv2.1 channel. Oncotarget, 59345-58. |
| 28432142 | not listed | Vullhorst, D., et al. 2017. Structural similarities between neuregulin 1–3 isoforms determine their subcellular distribution and signaling mode in central neurons. Journal of Neuroscience, 5232-5249. |
| 28119464 | not listed | Nystoriak, M.A., et al. 2017. Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel CaV1.2 and vasoconstriction during acute hyperglycemia and diabetes. Science Signaling, eaaf9647. |
| 26503721 | not listed | Thiffault, I., et al. 2015. A novel epileptic encephalopathy mutation in KCNB1 disrupts Kv2.1 ion selectivity, expression, and localization.. The Journal of General Physiology, 399-410. |
| 25164438 | 1:500 | Torkamani, A., et al. 2014. De novo KCNB1 mutations in epileptic encephalopathy.. Annals of Neurology, 529-40. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 36842733 | not listed | Markandeya, Y.S., et al. 2023. Caveolin-3 and Caveolae Regulate Ventricular Repolarization. Journal of Molecular and Cellular Cardiology, 38-49. |
| 33132203 | 2 ug/mL | Hawkins,N.A., et al. 2021. Epilepsy and neurobehavioral abnormalities in mice with a dominant-negative KCNB1 pathogenic variant. Neurobiology of Disease, 105141. |
| 33393091 | 1:200 | Zhou, L., et al. 2020. Transient receptor potential vanilloid 4 activation inhibits the delayed rectifier potassium channels in hippocampal pyramidal neurons: An implication in pathological changes following pilocarpine-induced status epilepticus. Journal of Neuroscience Research, 914-26. |
| 33333928 | not listed | Song, M.Y., et al. 2020. Tyrosine Phosphorylation of the Kv2. 1 Channel Contributes to Injury in Brain Ischemia. International Journal of Molecular Sciences, 9538. |
| 29265365 | not listed | Chao, R.Y., et al. 2018. Defective trafficking of Kv2.1 channels in MPTP-induced nigrostriatal degeneration. Journal of Neurochemistry, 483-97. |
| 28504671 | 1:5 (supe) | Fletcher, E.V., et al. 2017. Reduced sensory synaptic excitation impairs motor neuron function via Kv2.1 in spinal muscular atrophy. Nature Neuroscience, 905-16. |
| 26538660 | not listed | Bishop, H.I., et al. 2015. Distinct Cell- and Layer-Specific Expression Patterns and Independent Regulation of Kv2 Channel Subtypes in Cortical Pyramidal Neurons.. Journal of Neuroscience, 14922-42. |
| 26027736 | not listed | Vullhorst, D., et al. 2015. A negative feedback loop controls NMDA receptor function in cortical interneurons via neuregulin 2/ErbB4 signalling.. Nature Communications, 7222. |
| 25670860 | 1:2 (supe) | Nieves-Cintrón, M., et al. 2015. Selective down-regulation of KV2.1 function contributes to enhanced arterial tone during diabetes.. The Journal of Biological Chemistry, 7918-29. |
| 24494598 | not listed | Speca, D.J., et al. 2014. Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability.. Genes, Brain and Behavior, 394-408. |
| 20853508 | not listed | Hermanstyne, T.O., et al. 2010. Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice.. Journal of Comparative Neurology, 4298-310. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 36545239 | 1:800 | Li, X., et al. 2022. Intrathecal Administration of the Fat-mass and Obesity-associated Protein Inhibitor Mitigates Neuropathic Pain in Female Rats. Translational Perioperative and Pain Medicine, 478-487. |
| 33333928 | not listed | Song, M.Y., et al. 2020. Tyrosine Phosphorylation of the Kv2. 1 Channel Contributes to Injury in Brain Ischemia. International Journal of Molecular Sciences, 9538. |
| 31594866 | 10 µg/mL | Kirmiz, M., et al. 2019. Neuronal ER–plasma membrane junctions organized by Kv2–VAP pairing recruit Nir proteins and affect phosphoinositide homeostasis. Journal of Biological Chemistry, 17735-57. |
| 31240601 | 1:1000 | Vullhorst, D., et al. 2019. NMDA receptors regulate neuregulin 2 binding to ER-PM junctions and ectodomain release. . Molecular neurobiology, 8345-8363. |
| 28768770 | not listed | Wu, Y., et al. 2017. NMDA receptors mediate leptin signaling and regulate potassium channel trafficking in pancreatic β-cells. Journal of Biological Chemistry, 15512-24. |
| 28432142 | not listed | Vullhorst, D., et al. 2017. Structural similarities between neuregulin 1–3 isoforms determine their subcellular distribution and signaling mode in central neurons. Journal of Neuroscience, 5232-5249. |
| 22675541 | not listed | Manning, C.F., et al. 2012. Benefits and pitfalls of secondary antibodies: why choosing the right secondary is of primary importance.. PLoS One, e38313. |
| 20853508 | not listed | Hermanstyne, T.O., et al. 2010. Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice.. Journal of Comparative Neurology, 4298-310. |
| Additional Publications: Unspecified | ||
| PMID | Publication | |
| 35238051 | Colecraft, H.M., et al. 2022. Controlling ion channel function with renewable recombinant antibodies. The Journal of Physiology, 2023-36. | |
| 26890139 | Frazzini, V., et al. 2016. Altered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer''s disease mouse model.. Cell Death & Disease, e2100. | |
| 26240432 | Peltola, M.A., et al. 2016. AMIGO-Kv2.1 Potassium Channel Complex Is Associated With Schizophrenia-Related Phenotypes.. Schizophrenia Bulletin, 191-201. | |
| 26453299 | Wu, Y., et al. 2015. Concerted Trafficking Regulation of Kv2.1 and KATP Channels by Leptin in Pancreatic β-Cells.. The Journal of Biological Chemistry, 29676-90. | |
| 26442584 | Cobb, M.M., et al. 2015. Cell Cycle-dependent Changes in Localization and Phosphorylation of the Plasma Membrane Kv2.1 K+ Channel Impact Endoplasmic Reticulum Membrane Contact Sites in COS-1 Cells.. The Journal of Biological Chemistry, 29189-201. | |
| 26205295 | El Gebeily, G., et al. 2015. Estrogen regulation of the transient outward K(+) current involves estrogen receptor α in mouse heart.. Journal of Molecular and Cellular Cardiology, 85-94. | |
| 26115091 | He, K., et al. 2015. Regulation of Pro-Apoptotic Phosphorylation of Kv2.1 K+ Channels.. PLoS One, e0129498. | |
| 25908859 | Fox, P.D., et al. 2015. Induction of stable ER-plasma-membrane junctions by Kv2.1 potassium channels.. Journal of Cell Science, 2096-105. | |
| 25568127 | Liu, J., et al. 2015. Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation.. Journal of Neuroscience, 352-65. | |
| 25525262 | Ednie, A.R., et al. 2015. Reduced sialylation impacts ventricular repolarization by modulating specific K+ channel isoforms distinctly.. The Journal of Biological Chemistry, 2769-83. | |
| 25182224 | Jensen, C.S., et al. 2015. Live-cell imaging of post-golgi transport vesicles in cultured hippocampal neurons.. Cell Molecular Neurobiology, 123-35. | |
| 25674050 | Moutal, A., et al. 2014. Differential neuroprotective potential of CRMP2 peptide aptamers conjugated to cationic, hydrophobic, and amphipathic cell penetrating peptides.. Frontiers in Neuroscience, 471. | |
| 25260053 | Krasowska, E., et al. 2014. Aberrant location of inhibitory synaptic marker proteins in the hippocampus of dystrophin-deficient mice: implications for cognitive impairment in duchenne muscular dystrophy.. PLoS One, e108364. | |
| 25220706 | Siddoway, B., et al. 2014. Potassium channel Kv2.1 is regulated through protein phosphatase-1 in response to increases in synaptic activity.. Neuroscience Letters, 142-7. | |
| 24928958 | McCord, M.C., et al. 2014. Syntaxin-binding domain of Kv2.1 is essential for the expression of apoptotic K+ currents.. The Journal of Physiology, 3511-21. | |
| 24723263 | Dufour, M.A., et al. 2014. Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development.. Journal of Neuroscience Research, 981-99. | |
| 24647953 | Shah, N.H., et al. 2014. Cyclin e1 regulates Kv2.1 channel phosphorylation and localization in neuronal ischemia.. Journal of Neuroscience, 4326-31. | |
| 24606584 | Kirizs, T., et al. 2014. Distinct axo-somato-dendritic distributions of three potassium channels in CA1 hippocampal pyramidal cells.. European Journal of Neuroscience, 1771-83. | |
| 24597762 | Wang, C.Y., et al. 2014. GDF15 regulates Kv2.1-mediated outward K+ current through the Akt/mTOR signalling pathway in rat cerebellar granule cells.. Biochemical Journal, 35-47. | |
| 24569993 | Jensen, C.S., et al. 2014. Specific sorting and post-Golgi trafficking of dendritic potassium channels in living neurons.. The Journal of Biological Chemistry, 10566-81. | |
| 24494598 | Speca, D.J., et al. 2014. Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability.. Genes, Brain and Behavior, 394-408. | |
| 24477962 | King, A.N., et al. 2014. A unique ion channel clustering domain on the axon initial segment of mammalian neurons.. Journal of Comparative Neurology, 2594-608. | |
| 24445605 | Hund, T.J., et al. 2014. β(IV)-Spectrin regulates TREK-1 membrane targeting in the heart.. Cardiovascular Research, 166-75. | |
| 24431441 | Maguire, E.P., et al. 2014. Tonic inhibition of accumbal spiny neurons by extrasynaptic α4βδ GABAA receptors modulates the actions of psychostimulants.. Journal of Neuroscience, 823-38. | |
| 24375641 | Lopez-Izquierdo, A., et al. 2014. The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization.. American Journal of Physiology-Heart and Circulatory Physiology, H747-54. | |
| 23443966 | Pirger, Z., et al. 2014. Voltage-gated membrane currents in neurons involved in odor information processing in snail procerebrum.. Brian Structure and Function, 673-82. | |
| 24094875 | Cservenák, M., et al. 2013. Thalamic neuropeptide mediating the effects of nursing on lactation and maternal motivation.. PsychoneuroEndocrinology, 3070-84. | |
| 24086760 | Shepherd, A.J., et al. 2013. Chemokine co-receptor CCR5/CXCR4-dependent modulation of Kv2.1 channel confers acute neuroprotection to HIV-1 glycoprotein gp120 exposure.. PLoS One, e76698. | |
| 23918396 | McCord, M.C., et al. 2013. Convergent Ca2+ and Zn2+ signaling regulates apoptotic Kv2.1 K+ currents.. Proceedings of the National Academy of Science of the United States of America, 13988-93. | |
| 23878373 | Guan, D., et al. 2013. Kv2 channels regulate firing rate in pyramidal neurons from rat sensorimotor cortex.. The Journal of Physiology, 4807-25. | |
| 23857585 | Amako, Y., et al. 2013. Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosis.. The Journal of Biological Chemistry, 24753-63. | |
| 23458708 | Mavlyutov, T.A., et al. 2013. Lack of sigma-1 receptor exacerbates ALS progression in mice.. Neuroscience, 129-34. | |
| 23332758 | Kourrich, S., et al. 2013. Dynamic interaction between sigma-1 receptor and Kv1.2 shapes neuronal and behavioral responses to cocaine.. Cell, 236-47. | |
| 23325261 | Fox, P.D., et al. 2013. Regulation of Kv2.1 K(+) conductance by cell surface channel density.. Journal of Neuroscience, 1259-70. | |
| 23223293 | Shepherd, A.J., et al. 2012. Distinct modifications in Kv2.1 channel via chemokine receptor CXCR4 regulate neuronal survival-death dynamics.. Journal of Neuroscience, 17725-39. | |
| 23197740 | Tsantoulas, C., et al. 2012. Sensory neuron downregulation of the Kv9.1 potassium channel subunit mediates neuropathic pain following nerve injury.. Journal of Neuroscience, 17502-13. | |
| 23115240 | Smith, K.E., et al. 2012. Functional analysis of missense mutations in Kv8.2 causing cone dystrophy with supernormal rod electroretinogram.. The Journal of Biological Chemistry, 43972-83. | |
| 22745487 | Norris, C.A., et al. 2012. Regulation of neuronal proapoptotic potassium currents by the hepatitis C virus nonstructural protein 5A.. Journal of Neuroscience, 8865-70. | |
| 22612819 | Menegola, M., et al. 2012. The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice.. Epilepsia, 142-9. | |
| 22593583 | Al-Owais, M.M., et al. 2012. Carbon monoxide mediates the anti-apoptotic effects of heme oxygenase-1 in medulloblastoma DAOY cells via K+ channel inhibition.. The Journal of Biological Chemistry, 24754-64. | |
| 22433979 | Kinoshita, M., et al. 2012. Sigma-1 receptor alters the kinetics of Kv1.3 voltage gated potassium channels but not the sensitivity to receptor ligands.. Brain Research, 1-9. | |
| 22411134 | Dai, X.Q., et al. 2012. The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function.. Diabetologia, 1709-20. | |
| 22118516 | Zhou, M.H., et al. 2012. Cholesterol enhances neuron susceptibility to apoptotic stimuli via cAMP/PKA/CREB-dependent up-regulation of Kv2.1.. Journal of Neurochemistry, 502-14. | |
| 22106938 | Song, M.Y., et al. 2012. Dynamic modulation of the kv2.1 channel by SRC-dependent tyrosine phosphorylation.. Journal of Proteome Research, 1018-26. | |
| 22056818 | Peltola, M.A., et al. 2012. AMIGO is an auxiliary subunit of the Kv2.1 potassium channel.. EMBO Reports, 1293-9. | |
| 22006306 | Ikematsu, N., et al. 2011. Phosphorylation of the voltage-gated potassium channel Kv2.1 by AMP-activated protein kinase regulates membrane excitability.. Proceedings of the National Academy of Science of the United States of America, 18132-7. | |
| 21911612 | Joseph, B.K., et al. 2011. Postsynaptic density-95 scaffolding of Shaker-type K⁺ channels in smooth muscle cells regulates the diameter of cerebral arteries.. The Journal of Physiology, 5143-52. | |
| 21832084 | Brittain, J.M., et al. 2011. Neuroprotection against traumatic brain injury by a peptide derived from the collapsin response mediator protein 2 (CRMP2).. The Journal of Biological Chemistry, 37778-92. | |
| 21712386 | Cerda, O., et al. 2011. Activity-dependent phosphorylation of neuronal Kv2.1 potassium channels by CDK5.. The Journal of Biological Chemistry, 28738-48. | |
| 21671801 | Mihelec, M., et al. 2011. Long-term preservation of cones and improvement in visual function following gene therapy in a mouse model of leber congenital amaurosis caused by guanylate cyclase-1 deficiency.. Human Gene Therapy, 1179-90. | |
| 21518833 | Plant, L.D., et al. 2011. SUMO modification of cell surface Kv2.1 potassium channels regulates the activity of rat hippocampal neurons. Journal of General Physiology, 441-54. | |
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