Western Blot of stimulated HEK 293 cells showing specific immunolabeling of IKK-gamma in Interleukin 1.
Anti-IKK gamma (C-terminal) Antibody
Bulk Order Anti-IKK gamma (C-terminal) Antibody
Pro-inflammatory cytokines activate the transcription factor NF-kappaB by stimulating the activity of a protein kinase that phosphorylates IkappaB, an inhibitor of NF-kappaB, at sites that trigger its ubiquitination and degradation. A large, cytokine-responsive IkappaB kinase (IKK) complex contains 2 subunits, IKK-alpha and IKK-beta, which are protein kinases whose function is needed for NF-kappaB activation by pro-inflammatory stimuli. IKK is composed of similar amounts of IKK-alpha, IKK-beta, which are differentially processed forms of a third subunit, IKK-gamma. IKK-gamma interacts preferentially with IKK-beta and is required for the activation of the IKK complex.
Antigen Affinity Purified
Synthetic peptide corresponding to amino acids from the C-terminal region of human IKK gamma protein
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
PBS + 0.02% NaN3
WB Brain: 1:500-1:1000
Reacts with the C-terminal region of human IKK gamma protein. Recognizes both human isoforms.
Western blots performed on each lot.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
After date of receipt, stable for at least 1 year at -20°C.
IKBKG, IkB kinase associated protein 1, NEMO, IkB kinase subunit gamma, AMCBX1, FIP3, Ikbkg, IKKAP1, IKKg, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma, NF kappa B essential modifier, IP