Anti-GLUT10 Antibody

Name: Anti-GLUT10 Antibody
Brand: PhosphoSolutions
SKU: 24372
Price: 415.0 USD
Availability: InStock

from PhosphoSolutions

Our GLUT10 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat GLUT10 and is antigen affinity purified. It is great for use in WB, IHC.

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Applications

IHC, WB

Host Species

Rabbit

Format

Antigen Affinity Purified

Gene Name

SLC2A10

Go to Full Product Details

Immunohistochemistry of mouse inner ear frozen sections showing specific staining of GLUT10 at 1:200 dilution. Sections were incubated with secondary (anti-rabbit Cy3, 1:400) RT 1 hr. Slides mounted with fluoromont G and examined under a confocal microscope. Strong immunoreactivity (red) is observed in the inner and outer hair cells and basilar membrane. Spiral ganglion neurons display moderate staining.

Western Blot showing specific immunolabeling of GLUT10 in Lane 1: 10ug of protein from liver Lane 2: 10ug of protein from cochlea (E18) Lane 3: 10ug of protein from cochlea (P7) Lane 4: 10ug of protein from cochlea (P10) Lane 5: 10ug of protein from cochlea (P14) Lane 6: 10ug of protein from cochlea (P17) Lane 7: 10ug of protein from cochlea (P60) Lane 8: 10ug of protein from cochlea (1 Year).

Western Blot of NCI-H1299 non-small cell lung tumor cells transfected with the eukaryotic expression vectors pcDNA3.1/V5 (lanes 1,2), pCMV-GLUT10 (lanes 3,4), and pCMV-GLUT1 (lanes 5,6) showing specific immunolabeling of GLUT10.

Immunohistochemistry of mouse inner ear frozen sections showing specific staining of GLUT10 at 1:200 dilution. Sections were incubated with secondary (anti-rabbit Cy3, 1:400) RT 1 hr. Slides mounted with fluoromont G and examined under a confocal microscope. Strong immunoreactivity (red) is observed in the inner and outer hair cells and basilar membrane. Spiral ganglion neurons display moderate staining.

Title: 100 µL

Variant

Price:

$415

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Bulk Order Anti-GLUT10 Antibody

Product Details

Target

GLUT10

Target Description

Non-insulin-dependent diabetes mellitus (NIDDM) is a multifactoral disease with both environmental and genetics causes. Genome-wide screening procedures have identified several susceptibility loci for NIDDM within the human genome. A putative sugar transporter that has been localized to human chromosome 20q12-q13.1, one of the genomic loci associated with NIDDM. Because of the strong resemblance of this novel protein to members of the mammalian facilitative glucose transporter family (GLUT), the protein is known as GLUT10 (HGMW-approved gene symbol SLC2A10). Data suggests that GLUT10 an excellent candidate for a susceptibility gene involved in NIDDM. In addition, mouse whole genome microarray data shows GLUT1 and GLUT10 have the highest expression of the GLUT10 family in mouse cochlea. Ito et al showed vascular endothelial cells, basal cell layer of the stria vascularis and satellite cells contained GLUT1. However, this is the first report that GluT10 exists in the mouse cochlea. Current studies are investigating the location of GLUT10 expression in the mouse, rat, GP and monkey cochlea.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

IHC, WB

Host Species

Rabbit

Gene Name

SLC2A10

Antigen

Synthetic peptide corresponding to amino acids from an internal sequence of the human Ly-6k protein

Species Reactivity

Human, Mouse, Rat

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000
IHC: 1:100-1:250

Specificity

Residues with internal residues of human, mouse and rat GLUT10 protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

SLC2A10, Solute carrier family 2, facilitated glucose transporter member 10, Glucose transporter type 10

UniProt Details

UniProt (Human): O95528
UniProt (Immunogen Species): O95528

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Anti-GLUT10 Antibody

Our GLUT10 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat GLUT10 and is antigen affinity purified. It is great for use in WB, IHC.