Anti-GluR1-Subunit (Ser845) Antibody


Our Anti-GluR1-Subunit (Ser845) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects mouse and rat GluR1-Subunit (Ser845) and is antigen affinity purified from pooled serum. It is great for use in WB, IHC.

Primary Antibody
Mouse, Rat
Human, Non-Human Primate
IHC, WB
Rabbit
Antigen Affinity Purified from Pooled Serum
GRIA1
100 kDa

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Anti-GluR1-Subunit (Ser845) Antibody
SKU: p1160-845

Volume: 150 µL
Price:
Sale price$399


Bulk Order Anti-GluR1-Subunit (Ser845) Antibody

Product Specific References for Applications and Species

Immunocytochemistry: Mouse
PMID Dilution Publication
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Western Blot: Mouse
PMID Dilution Publication
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28167675 1:1000 Andrade, E.C., et al. 2017. ARPP-16 is a striatal-enriched inhibitor of protein phosphatase 2A regulated by microtubule-associated serine/threonine kinase 3 (Mast 3 kinase). Journal of Neuroscience, pp.4559-15.
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25173217 1:1000 Mango, D., et al. 2014. Adenosine A1 receptor stimulation reduces D1 receptor-mediated GABAergic transmission from striato-nigral terminals and attenuates l-DOPA-induced dyskinesia in dopamine-denervated mice. Experimental Neurology, 261, pp.733-743.
25136890 1:1000 Squillace, M., et al. 2014. Dysfunctional dopaminergic neurotransmission in asocial BTBR mice. Translational Psychiatry, 4(8), p.e427.
25115542 not listed Wang, J., et al. 2014. Fluoxetine Improves Behavioral Performance by Suppressing the Production of Soluble β-Amyloid in APP/PS1 Mice. Current Alzheimer Research, 11(7), 672-680.
24920629 not listed Meyer, D.A., et al. 2014. Ischemic stroke injury is mediated by aberrant Cdk5. The Journal of Neuroscience, 34(24), 8259-8267.
24907515 not listed Mao, L.M., et al. 2014. Propofol selectively alters GluA1 AMPA receptor phosphorylation in the hippocampus but not prefrontal cortex in young and aged mice. European Journal of Pharmacology, 738, 237-244.
23303927 not listed Shen, Y., et al. 2013. Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanism. Journal of Neuroscience 33(2):464-72.
22753408 1:1000 Santini, E., et al. 2012. Dopamine- and cAMP-regulated phosphoprotein of 32-kDa (DARPP-32)-dependent activation of extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin complex 1 (mTORC1) signaling in experimental parkinsonism. Journal of Biological Chemistry 287(33):27806-12.
21946266 not listed Errico, F., et al. 2011. Higher free D-aspartate and N-methyl-D-aspartate levels prevent striatal depotentiation and anticipate L-DOPA-induced dyskinesia. Experimental Neurology, 232(2), pp.240-250.
20720111 1:1000 Napolitano, F., et al. 2010. Role of aberrant striatal dopamine D1 receptor/cAMP/protein kinase A/DARPP32 signaling in the paradoxical calming effect of amphetamine. Journal of Neuroscience, 30(33), pp.11043-11056.
20554878 1:500 Sears, R.M., et al. 2010. Regulation of Nucleus Accumbens Activity by the Hypothalamic Neuropeptide Melanin-Concentrating Hormone. Journal of Neuroscience, 30: 8263-8273.
19666609 not listed Rebholz, H., et al. 2009. CK2 negatively regulates G s signaling. PNAS, 106: 14096-14101.
19622833 1:750 Santini, E., et al. 2009. Inhibition of mTOR Signaling in Parkinson’s Disease Prevents L-DOPA–Induced Dyskinesia. Science Singalling, Jul 2009; 2: ra36.
19017804 not listed Meyer, D.A., et al. 2008. Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology. PNAS, 105: 18561 - 18566.
18923023 1:250 Nishi, A., et al. 2008. Distinct Roles of PDE4 and PDE10A in the Regulation of cAMP/PKA Signaling in the Striatum. Journal of Neuroscience, 28: 10460– 10471.
18417701 1:500 Sun, X., et al. 2008. Acute and chronic dopamine receptor stimulation modulates AMPA receptor trafficking in nucleus accumbens neurons cocultured with prefrontal cortex neurons. Journal of Neuroscience Apr 16;28(16):4216-30.
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Western Blot: Rat
PMID Dilution Publication
35835216not listedThomas, R., et al. 2022. Integrated regulation of PKA by fast and slow neurotransmission in the nucleus accumbens controls plasticity and stress responses. The Journal of biological chemistry, 102245.
34592633 1:1000 Del Angel, Y.C., et al. 2021. Down-regulation of AMPA receptors and long-term potentiation during early epileptogenesis. Epilepsy and Behavior, 124, p. 108320.
31994358 1:500 Mao, L.M., et al. 2018. Upregulation of AMPA receptor GluA1 phosphorylation by blocking adenosine A1 receptors in the male rat forebrain. Brain and Behavior, p.e01543.
29432883 not listed Mao, L.M., et al. 2018. Regulation of Phosphorylation of AMPA Glutamate Receptors by Muscarinic M4 Receptors in the Striatum In vivo. Neuroscience, 375, pp.84-93.
29417763 not listed Suzuki, K., et al. 2018. Combined treatment with a selective PDE10A inhibitor TAK‐063 and either haloperidol or olanzapine at subeffective doses produces potent antipsychotic‐like effects without affecting plasma prolactin levels and cataleptic responses in rodents. Pharmacology Research & Perspectives, 6(1).
29242119 not listed Xue, B., et al. 2017. Pharmacological modulation of AMPA receptor phosphorylation by dopamine and muscarinic receptor agents in the rat medial prefrontal cortex. European Journal of Pharmacology. 2017 Dec 11;820:45-52.
28757258 1:1000 Tronci, E., et al. 2017. BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to l-DOPA-induced dyskinesia in 6-OHDA-lesioned rats. Experimental Neurology Nov;297:73-8.
28578480 not listed Lameth, J., et al. 2017. Acute Neuroinflammation Promotes Cell Responses to 1800 MHz GSM Electromagnetic Fields in the Rat Cerebral Cortex. Neurotoxicity Research, pp.1-16.
28167675 1:1000 Andrade, E.C., et al. 2017. ARPP-16 is a striatal-enriched inhibitor of protein phosphatase 2A regulated by microtubule-associated serine/threonine kinase 3 (Mast 3 kinase). Journal of Neuroscience, pp.4559-15.
27844053 1:5000 Hollis, F., et al. 2016. Involvement of CRFR1 in the basolateral amygdala in the immediate fear extinction deficit. eNeuro, 3(5).
27338925 1:1000 Xue, B., et al. 2016. Amphetamine elevates phosphorylation of eukaryotic initiation factor 2α (eIF2α) in the rat forebrain via activating dopamine D1 and D2 receptors. Brain Research, 1646, pp.459-466.
27060412 not listed Xue, B., et al. 2017. Integrated regulation of AMPA glutamate receptor phosphorylation in the striatum by dopamine and acetylcholine. Neuropharmacology, 112, pp.57-65.
26706598 not listed O’Leary, H., et al. 2016. Enhanced long term potentiation and decreased AMPA receptor desensitization in the acute period following a single kainate induced early life seizure. Neurobiology of Disease, 87, 134-144.
25689263 1:1000 Mao, L.M., et al. 2015. Dynamic increases in AMPA receptor phosphorylation in the rat hippocampus in response to amphetamine. Journal of Neurochemistry. Jun;133(6):795-805.
25525190 not listed Suzuki, K., et al. 2015. In Vivo Pharmacological Characterization of TAK-063, a Potent and Selective Phosphodiesterase 10A Inhibitor with Antipsychotic-Like Activity in Rodents. Journal of Pharmacology and Experimental Therapeutics, 352:471-479.
24920629 not listed Meyer, D.A., et al. 2014. Ischemic stroke injury is mediated by aberrant Cdk5. The Journal of Neuroscience, 34(24), 8259-8267.
24780380 1:500 Bernard, P.B., et al. 2014. Necessary, but not sufficient: insights into the mechanisms of mGluR mediated long-term depression from a rat model of early life seizures. Neuropharmacology, 84, 1-12.
24231469 1:1000 Xue, B., et al. 2014. Rapid and sustained GluA1 S845 phosphorylation in synaptic and extrasynaptic locations in the rat forebrain following amphetamine administration. Neurochemistry International, 64, 48-54.
23303927 not listed Shen, Y., et al. 2013. Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanism. Journal of Neuroscience 33(2):464-72.
20554878 1:500 Sears, R.M., et al. 2010. Regulation of Nucleus Accumbens Activity by the Hypothalamic Neuropeptide Melanin-Concentrating Hormone. Journal of Neuroscience, 30: 8263 - 8273.
18819923 1:1000 Davies, K.D., et al. 2008. Long Term Synaptic Depression That Is Associated with GluR1 Dephosphorylation but Not -Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Internalization. Journal of Biological Chemistry, 283: 33138 - 33146.
18417701 1:500 Sun, X., et al. 2008. Acute and chronic dopamine receptor stimulation modulates AMPA receptor trafficking in nucleus accumbens neurons cocultured with prefrontal cortex neurons. Journal of Neuroscience Apr 16;28(16):4216-30.
Western Blot: Turtle
PMID Dilution Publication
19261706 not listed Zheng, Z., et al. 2009. PKA Has a Critical Role in Synaptic Delivery of GluR1- and GluR4- Containing AMPARs During Initial Stages of Acquisition of In Vitro Classical Conditioning. Journal of Neurophysiology, 101: 2539 - 2549.

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