Name: Anti-DOPA Decarboxylase Antibody
Brand: PhosphoSolutions
SKU: 418-DDCH
Price: 415.0 USD
Availability: InStock

Our Anti-DOPA Decarboxylase rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects bovine, canine, guinea pig, human, rabbit, rat, and sheep DOPA Decarboxylase and is antigen affinity purified from pooled serum. It is great for use in WB.

Product Type

Primary Antibody

Species Reactivity

Bovine, Canine, Guinea Pig, Human, Rabbit, Rat, Sheep

Applications

WB

Host Species

Rabbit

Format

Antigen Affinity Purified from Pooled Serum

Gene Name

DDC

Molecular Weight

55 kDa

Go to Full Product Details

Western blot of 5 µg of bovine adrenal medulla lysate showing specific immunolabeling of the ~55 kDa DOPA decarboxylase protein.

Volume: 100 µL

Variant

Price:

$415

Quantity:

Bulk Order Anti-DOPA Decarboxylase Antibody

Product Details

Target

DOPA Decarboxylase

Target Description

DOPA decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).

Format

Antigen Affinity Purified from Pooled Serum

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Host Species

Rabbit

Gene Name

DDC

Molecular Weight

55 kDa

Antigen

Synthetic peptide from N-terminus region of human DOPA decarboxylase (DDC), conjugated to keyhole limpet hemocyanin (KLH).

Species Reactivity

Bovine, Canine, Guinea Pig, Human, Rabbit, Rat, Sheep

Antibody Registry ID

AB_2492073

Storage

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Physical State

Liquid

Production Notes

Prepared from pooled rabbit serum by affinity purification using an AminoLink® Plus column matrix to which purified, recombinant bovine DDC was coupled.

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Dilution Ranges

WB: 1:1000
WB Brain: 1:1000

Conjugate

Unconjugated

Specificity

Specific for endogenous levels of the ~55 kDa DDC protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

AADC antibody, Aromatic L Amino Acid Decarboxylase antibody, Aromatic-L-amino-acid decarboxylase antibody, DDC antibody, DDC_HUMAN antibody, DOPA decarboxylase (aromatic L-amino acid decarboxylase) antibody, DOPA decarboxylase antibody

UniProt Details

UniProt (Human): P20711
UniProt (Immunogen Species): P20711

NCBI Gene ID

1644

Product Specific References for Applications and Species

Western Blot: Human

Western Blot: Human
PMID	Dilution	Publication
12065667	not listed	Waymire, J.C., et al. 2002. Lack of regulation of aromatic l‐amino acid decarboxylase in intact bovine chromaffin cells. Journal of Neurochemistry, 81(3), pp.589-593.

Product Specific Protocols

Western Blot Protocol: Download

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Anti-DOPA Decarboxylase Antibody

Our Anti-DOPA Decarboxylase rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects bovine, canine, guinea pig, human, rabbit, rat, and sheep DOPA Decarboxylase and is antigen affinity purified from pooled serum. It is great for use in WB.