Anti-CRMP2 (Ser-522), Phosphospecific Antibody

Our CRMP2 (Ser-522) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat CRMP2 (Ser-522) and is antigen affinity purified. It is great for use in WB, ICC.

SKU: CP2191

Volume: 100 µL
Sale price$329

Product Specific References for Applications and Species

Immunocytochemistry: Human
PMID Dilution Publication
33401710not listedPaik, S, et al. 2021. Somatostatin Ameliorates β-Amyloid-Induced Cytotoxicity via the Regulation of CRMP2 Phosphorylation and Calcium Homeostasis in SH-SY5Y Cells. Biomedicines, 27.
Immunocytochemistry: Rat
PMID Dilution Publication
28809766not listedMoutal, A, et al. 2017. CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide. Pain, 2301-2319.
Immunohistochemistry: Mouse
PMID Dilution Publication
342978161:200Yamazaki, Y, et al. 2022. Requirement of CRMP2 Phosphorylation in Neuronal Migration of Developing Mouse Cerebral Cortex and Hippocampus and Redundant Roles of CRMP1 and …. Cerebral cortex, 520-527.
329732421:1000Nishijima, E, et al. 2020. Topical ripasudil stimulates neuroprotection and axon regeneration in adult mice following optic nerve injury. Scientific reports, 15709.
321565711:200Yamazaki, Y, et al. 2020. Phosphorylation of CRMP2 is required for migration and positioning of Purkinje cells: Redundant roles of CRMP1 and CRMP4. Brain research, 146762.
303751271:200Togashi, K, et al. 2019. Genetic suppression of collapsin response mediator protein 2 phosphorylation improves outcome in methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson’s model mice. Genes to cells : devoted to molecular & cellular mechanisms, 31-40.
28660485not listedMoutal, A, et al. 2018. CRMP2 Phosphorylation Drives Glioblastoma Cell Proliferation. Molecular neurobiology, 4403-4416.
Immunohistochemistry: Rat
PMID Dilution Publication
32571373not listedMoutal, A, et al. 2020. Differential expression of Cdk5-phosphorylated CRMP2 following a spared nerve injury. Molecular brain, 97.
27917413not listedMoutal, A, et al. 2016. Efficacy of ( S)-Lacosamide in preclinical models of cephalic pain. Pain reports, e565.
Western Blot: Human
PMID Dilution Publication
334017101:1000Paik, S, et al. 2021. Somatostatin Ameliorates β-Amyloid-Induced Cytotoxicity via the Regulation of CRMP2 Phosphorylation and Calcium Homeostasis in SH-SY5Y Cells. Biomedicines, 17.
30816227not listedDuciel, L, et al. 2019. Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) promotes the aggressiveness of human uveal melanoma through dephosphorylation of CRMP2. Scientific reports, 2990.
299268351:2000Mokhtar, S, et al. 2018. Amyloid-beta-dependent phosphorylation of collapsin response mediator protein-2 dissociates kinesin in Alzheimer's disease. Neural regeneration research, 1066-1080.
Western Blot: Mouse
PMID Dilution Publication
371746871:1500Brustovetsky, T, et al. 2023. CRMP2 Participates in Regulating Mitochondrial Morphology and Motility in Alzheimer's Disease. Cells, 1287.
355899151:1000Yazawa, A, et al. 2022. Effects of Lanthionine Ketimine-5-Ethyl Ester on the α-Synucleinopathy Mouse Model. Neurochemical Research, 2373-2382.
348313951:1500Brustovestsky, T, et al. 2021. Involvement of CRMP2 in Regulation of Mitochondrial Morphology and Motility in Huntington's Disease. Cells, 3172.
346857601:1500Brustovestsky, T, et al. 2021. CRMP2 Is Involved in Regulation of Mitochondrial Morphology and Motility in Neurons. Cells, 2781.
31795726not listedMoutal, A, et al. 2019. Neuronal Conditional Knockout of Collapsin Response Mediator Protein 2 Ameliorates Disease Severity in a Mouse Model of Multiple Sclerosis. ASN Neuro, 44943.
28648892not listedLiu, R, et al. 2017. ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress. DNA repair, 29-34.
Western Blot: Rat
PMID Dilution Publication
384716251:2500Kim, K, et al. 2024. Insular cortex stimulation alleviates neuropathic pain through changes in the expression of collapsin response mediator protein 2 involved in synaptic plasticity. Neurobiology of Disease, 106466.
353344121:1000Li, Y, et al. 2022. CRMP2 Modulates Mossy Fiber Sprouting in Dentate Gyrus of Pilocarpine Induced Rat Model of Epilepsy. Biochemical and Biophysical Research Communications, 141-147.
365648531:1000Jiang, YP, et al. 2022. Neuronal CRMP2 phosphorylation inhibition by the flavonoid, naringenin, contributes to the reversal of spinal sensitization and arthritic pain improvement. Arthritis research & therapy, 277.
31680630not listedMoutal, A, et al. 2019. Evaluation of edonerpic maleate as a CRMP2 inhibitor for pain relief. Channels (Austin, Tex.), 498-504.
31080913not listedMoutal, A, et al. 2019. Cdk5-mediated CRMP2 phosphorylation is necessary and sufficient for peripheral neuropathic pain. Neurobiology of pain (Cambridge, Mass.), 100022.
28767512not listedMoutal, A, et al. 2017. Dissecting the role of the CRMP2-neurofibromin complex on pain behaviors. Pain, 2203-2221.
26967696not listedMoutal, A, et al. 2016. (S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology. Pain reports, 1448-1463.

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