Anti-CASPR/Neurexin IV Antibody (K65/35)
Primary Antibody
Human, Mouse, Rat
K65/35
IHC, IP, WB
Mouse
Purified
Cntnap1 Caspr Nrxn4
220 kDa
![Immunoblots on brain membranes prepared from whole rat (RBM) and mouse (MBM) brain, and from human cerebral cortex [HBM(Cx)], cerebellum [HBM(Cb)], and hippocampus [HBM(H)].](http://www.phosphosolutions.com/cdn/shop/products/validation-image-73-001-k65-35-wb-3_{width}x.jpg?v=1686068441)
![EGFP expression (green) was absent in the optic nerves of [gfap] dnVAMP2 mice supplied DOX (DOX-ON) and prevalent in astrocytes in the optic nerves of [gfap] dnVAMP2 mice on a diet without DOX (DOX-OFF) from gestation through adulthood (P70). EGFP expression in astrocytes was also elevated for a DOX-ON diet through development with DOX_OFF for P40 to P70 (30 d DOX-OFF). The paranodal region labeled with Caspr1 (red). DNA labelled with DAPI (blue). Image from publication CC-BY-4.0. PMID:36302632](http://www.phosphosolutions.com/cdn/shop/products/75-001-k65-35-ihc-3_{width}x.jpg?v=1686068441)
Adult rat brain membrane immunoblot.
![Immunoblots on brain membranes prepared from whole rat (RBM) and mouse (MBM) brain, and from human cerebral cortex [HBM(Cx)], cerebellum [HBM(Cb)], and hippocampus [HBM(H)].](http://www.phosphosolutions.com/cdn/shop/products/validation-image-73-001-k65-35-wb-3_1024x.jpg?v=1686068441)
![EGFP expression (green) was absent in the optic nerves of [gfap] dnVAMP2 mice supplied DOX (DOX-ON) and prevalent in astrocytes in the optic nerves of [gfap] dnVAMP2 mice on a diet without DOX (DOX-OFF) from gestation through adulthood (P70). EGFP expression in astrocytes was also elevated for a DOX-ON diet through development with DOX_OFF for P40 to P70 (30 d DOX-OFF). The paranodal region labeled with Caspr1 (red). DNA labelled with DAPI (blue). Image from publication CC-BY-4.0. PMID:36302632](http://www.phosphosolutions.com/cdn/shop/products/75-001-k65-35-ihc-3_1024x.jpg?v=1686068441)
Product Specific References for Applications and Species
- Immunocytochemistry: Human | Mouse
- Immunohistochemistry: Gerbil | Human | Mouse | Rat
- Western Blot: Mouse
- Additional Publications: Unspecified
| Immunocytochemistry: Human | ||
| PMID | Dilution | Publication |
| 35417746 | 1:400 | Otani, Y., et al. 2022. Influence of Novel Readthrough Agents on Myelin Protein Zero Translation in the Peripheral Nervous System. Neuropharmacology, 109059. |
| 33097924 | not listed | García-León, J.A., et al. 2020. Generation of oligodendrocytes and establishment of an all-human myelinating platform from human pluripotent stem cells. Nature Protocols, 3716-3744. |
| 28512649 | 1:40 | Stratton, J.A., et al. 2017. Purification and Characterization of Schwann Cells from Adult Human Skin and Nerve. eNeuro, . |
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 35672149 | 1:1000 | Liu, H., et al. 2022. Direct Observation of Compartment-Specific Localization and Dynamics of Voltage-Gated Sodium Channels. The Journal of Neuroscience, 5482-5498. |
| 32125730 | not listed | Jarjour, A.A., et al. 2020. The formation of paranodal spirals at the ends of CNS myelin sheaths requires the planar polarity protein Vangl2. Glia, 1840-1858. |
| 29138759 | not listed | Browne, L., et al. 2017. Identification of persistent and resurgent sodium currents in spiral ganglion neurons cultured from the mouse cochlea.. Eneuro, . |
| 26406915 | 1:200 | Brügger, V., et al. 2015. HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins.. PLoS Biology, e1002258. |
| 25362473 | not listed | Ho, T.S., et al. 2015. A hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of Ranvier.. Nature Neuroscience, 1664-72. |
| 19261867 | 1:1000 | Sharkey, L.M., et al. 2009. The ataxia3 mutation in the N-terminal cytoplasmic domain of sodium channel Na(v)1.6 disrupts intracellular trafficking.. Journal of Neuroscience, 2733-2741. |
| 19013247 | 1:500 | O'Malley, H.A., et al. 2009. Loss of Na+ channel β2 subunits is neuroprotective in a mouse model of multiple sclerosis. . Molecular and Cellular Neuroscience, 143-155. |
| Immunohistochemistry: Gerbil | ||
| PMID | Dilution | Publication |
| 27110919 | not listed | Ko, K.W., et al. 2016. Serotonin modulates spike probability in the axon initial segment through HCN channels. Nature Neuroscience, 826-834. |
| 26556176 | 1:1000 | Seidl, A.H., et al. 2016. Systematic and differential myelination of axon collaterals in the mammalian auditory brainstem.. Glia, 487-494. |
| Immunohistochemistry: Human | ||
| PMID | Dilution | Publication |
| 20838243 | not listed | Howell, O.W., et al. 2010. Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis.. Journal of Neuropathology & Experimental Neurology, 1017-1033. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 37315917 | 1:500 | Seixas, AI, et al. 2023. A RhoA-mediated Biomechanical Response in Schwann Cells Modulates Peripheral Nerve Myelination. Progress in Neurobiology, 102481. |
| 36949148 | 1:5000 | Koskinen, M.K., et al. 2023. Node of Ranvier Remodeling in Chronic Psychosocial Stress and Anxiety. Neuropsychopharmacology, . |
| 36302632 | 1:50 | Santos, E.N., et al. 2022. Effects of Visual Deprivation on Remodeling of Nodes of Ranvier in Optic Nerve. eNeuro, . |
| 36273507 | 1:200 | Takahashi, K., et al. 2022. Brexpiprazole Prevents Colitis-Induced Depressive-Like Behavior Through Myelination in the Prefrontal Cortex. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 110666. |
| 35952494 | 1:400 | Silva Oliveira Junior, M., et al. 2022. Myelin repair is fostered by the corticosteroid medrysone specifically acting on astroglial subpopulations. EBioMedicine, 104204. |
| 35726031 | 1:200 | Malara, M., et al. 2022. SHANK3 Deficiency Leads to Myelin Defects in the Central and Peripheral Nervous System. Cellular and Molecular Life Sciences, 371. |
| 35246535 | 1:500 | Meschkat, M., et al. 2022. White matter integrity in mice requires continuous myelin synthesis at the inner tongue. Nature communications, 1163. |
| 35123326 | 1:200 | Takahashi, K., et al. 2022. Antidepressant effects of Enterococcus faecalis 2001 through the regulation of prefrontal cortical myelination via the enhancement of CREB/BDNF and NF-κB p65/LIF/STAT3 pathways in olfactory bulbectomized mice. Journal of Psychiatric Research, 137-148. |
| 34844642 | not listed | Hay, C.M., et al. 2021. The oligodendrocyte-enriched orphan G protein-coupled receptor Gpr62 is dispensable for central nervous system myelination. Neural development, 16(1), pp.1-13.. Neural development, . |
| 34648330 | 1:100 | Lezmy, J., et al. 2021. Astrocyte Ca 2+-evoked ATP release regulates myelinated axon excitability and conduction speed. Science, eabh2858. |
| 33605175 | 1:100 | Nonaka, M., et al. 2021. Behavioral and Myelin-Related Abnormalities after Blast-Induced Mild Traumatic Brain Injury in Mice. Journal of Neurotrauma, 1551-1571. |
| 33563723 | 1:100 | Prades, S., et al. 2021. Functional P2X 7 Receptors in the Auditory Nerve of Hearing Rodents Localize Exclusively to Peripheral Glia. Journal of Neuroscience, 2615-2629. |
| 33472865 | 1:200 | Alam, M.M., et al. 2021. Deficiency of Microglial Autophagy Increases the Density of Oligodendrocytes and Susceptibility to Severe Forms of Seizures. eNeuro, . |
| 33472075 | 1:200 | Cullen, C.L., et al. 2021. Periaxonal and nodal plasticities modulate action potential conduction in the adult mouse brain. Cell Reports, 108641. |
| 34825395 | 1:100 | Newville, J., et al. 2020. Persistent myelin abnormalities in a third trimester‐equivalent mouse model of fetal alcohol spectrum disorder. . Alcoholism: Clinical and Experimental Research, 77-86. |
| 33335032 | 1:100 | Yang, S.M., et al. 2020. Neuron class-specific responses govern adaptive myelin remodeling in the neocortex. Science, eabd2109. |
| 32557778 | 1:200 | Ferreira, S., et al. 2020. Amyloidosis is associated with thicker myelin and increased oligodendrogenesis in the adult mouse brain. . Journal of neuroscience research, 1905-1932. |
| 32170207 | 1:400 | Otani, Y., et al. 2020. Upregulation of large myelin protein zero leads to Charcot-Marie-Tooth disease-like neuropathy in mice. Communications Biology, 121. |
| 31769505 | 1:100 | Yu, Y., et al. 2020. Microglial Hv1 proton channels promote white matter injuries after chronic hypoperfusion in mice. Journal of Neurochemistry, 350-367. |
| 31933626 | 1:500 | Alshammari, M.A., et al. 2019. Changes in the Fluorescence Tracking of NaV1.6 Protein Expression in a BTBR T+Itpr3tf/J Autistic Mouse Model. Neural Plasticity, 4893103. |
| 31839007 | not listed | Aziz, N.M., et al. 2019. Spatiotemporal development of spinal neuronal and glial populations in the Ts65Dn mouse model of Down syndrome. Journal of Neurodevelopmental Disorders, 35. |
| 31641127 | 1:1000 | Djannatian, M., et al. 2019. Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS. Nature Communications, 4794. |
| 31285774 | 1:100 | Wang, M., et al. 2019. Astrocytic connexin 43 potentiates myelin injury in ischemic white matter disease. Theranostics, 4474-4493. |
| 29300891 | 1:300 | Scott, R., et al. 2019. Loss of Cntnap2 Causes Axonal Excitability Deficits, Developmental Delay in Cortical Myelination, and Abnormal Stereotyped Motor Behavior. Cereb Cortex, 586-597. |
| 30555556 | 1:100 | Qin, C., et al. 2018. Microglial TLR4-dependent autophagy induces ischemic white matter damage via STAT1/6 pathway. Theranostics, 5434-5451. |
| 30240044 | not listed | Liu, Y., et al. 2018. Distinct patterns of glia repair and remyelination in antibody‐mediated demyelination models of multiple sclerosis and neuromyelitis optica. . Glia, 2575-2588. |
| 30149050 | 1:500 | Smith, M.A., et al. 2018. Nodes of Ranvier in Glaucoma. Neuroscience, 104-118. |
| 29664021 | 1:250 | Srivastava, T., et al. 2018. A TLR/AKT/FoxO3 immune tolerance-like pathway disrupts the repair capacity of oligodendrocyte progenitors. Journal of Clinical Investigation, 2025-2041. |
| 29556031 | 1:500 | Hill, R.A., et al. 2018. Lifelong cortical myelin plasticity and age-related degeneration in the live mammalian brain. Nature Neuroscience, 683-695. |
| 29431744 | not listed | He, X., et al. 2018. A histone deacetylase 3-dependent pathway delimits peripheral myelin growth and functional regeneration. Nature Medicine, 338-351. |
| 28722234 | 1:50 | Manso, Y., et al. 2018. Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease. Glia, 34-46. |
| 28556945 | 1:500 | Davidson, N.L., et al. 2017. Leukemia/lymphoma-related factor (LRF) exhibits stage- and context-dependent transcriptional controls in the oligodendrocyte lineage and modulates remyelination. Journal of Neuroscience Research, 2391-2408. |
| 28193689 | 1:100 | Furusho, M., et al. 2017. Signaling by FGF Receptor 2, Not FGF Receptor 1, Regulates Myelin Thickness through Activation of ERK1/2-MAPK, Which Promotes mTORC1 Activity in an Akt-Independent Manner. Journal of Neuroscience, 2931-2946. |
| 28174059 | 1:1000 | Oshitari, T., et al. 2017. Alterations of myelin morphology and oligodendrocyte development in early stage of Alzheimer's disease mouse model. Neuroscience Letters, 102-106. |
| 28123356 | not listed | Yoshimura, T., et al. 2017. Developmental Changes in Expression of βIV Spectrin Splice Variants at Axon Initial Segments and Nodes of Ranvier. Frontiers in cellular neuroscience, 304. |
| 27775720 | 1:100 | Goebbels, S., et al. 2017. A neuronal PI(3,4,5)P 3-dependent program of oligodendrocyte precursor recruitment and myelination. Nature Neuroscience, 10-15. |
| 27448245 | 1:50 | Serwanski, D.R., et al. 2017. Heterogeneity of astrocyte and NG2 cell insertion at the node of ranvier.. Journal of Comparative Neurology, . |
| 27581456 | not listed | Marin, M.A., et al. 2016. Reassembly of excitable domains after CNS axon regeneration. Journal of Neuroscience, 36(35), pp.9148-9160.. Journal of Neuroscience, 9148-9160. |
| 26909021 | 1:500 | Alshammari, M.A., et al. 2016. Improved methods for fluorescence microscopy detection of macromolecules at the axon initial segment. . Frontiers in cellular neuroscience, 5. |
| 26724902 | 1:200 | Kawabata, S., et al. 2016. Grafted Human iPS Cell-Derived Oligodendrocyte Precursor Cells Contribute to Robust Remyelination of Demyelinated Axons after Spinal Cord Injury.. Stem Cell Reports, . |
| 26203142 | not listed | Zollinger, D.R., et al. 2015. The polarity protein Pals1 regulates radial sorting of axons. . Journal of Neuroscience, 10474-10484. |
| 25948259 | 1:1000 | Hirono, M., et al. 2015. BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells.. Journal of Neuroscience, 7082-7094. |
| 25362471 | not listed | Chang, K.J., et al. 2014. Glial ankyrins facilitate paranodal axoglial junction assembly.. Nature Neuroscience, 1673-81. |
| 25319708 | 1:100 | Xing, Y.L., et al. 2014. Adult neural precursor cells from the subventricular zone contribute significantly to oligodendrocyte regeneration and remyelination. . Journal of Neuroscience, 14128-14146. |
| 21958379 | not listed | Duflocq, A., et al. 2011. Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B.. BMC Biology, . |
| 20838243 | not listed | Howell, O.W., et al. 2010. Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis.. Journal of Neuropathology & Experimental Neurology, 1017-1033. |
| 18522848 | 1:600 | Windrem, M.S., et al. 2008. Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse.. Cell Stem Cell, 553-565. |
| Immunohistochemistry: Rat | ||
| PMID | Dilution | Publication |
| 37388725 | 1:100 | Hecker, K, et al. 2023. Different Binding and Pathogenic Effect of Neurofascin and Contactin-1 Autoantibodies in Autoimmune Nodopathies. Frontiers in Immunology, 1189734. |
| 36653191 | 1:1000 | Petrosyan, H.A., et al. 2023. AAV Vector Mediated Delivery of NG2 Function Neutralizing Antibody and Neurotrophin NT-3 Improves Synaptic Transmission, Locomotion, and Urinary Tract Function after Contusion Spinal Cord Contusion Injury in Adult Rats. The Journal of Neuroscience, . |
| 36163283 | 1:500 | Hari, K., et al. 2022. GABA Facilitates Spike Propagation Through Branch Points of Sensory Axons in the Spinal Cord. Nature Neuroscience, 1288-1299. |
| 30377733 | 1:400 | Greguske, E.A., et al. 2019. Calyx junction dismantlement and synaptic uncoupling precede hair cell extrusion in the vestibular sensory epithelium during sub-chronic 3,3'-iminodipropionitrile ototoxicity in the mouse. Archives of Toxicology, 417-434. |
| 30384417 | 1:500 | Mao, Y., et al. 2018. The Effects of a Combination of Ion Channel Inhibitors in Female Rats Following Repeated Mild Traumatic Brain Injury. International Journal of Molecular Science, 3408. |
| 28806920 | 1:500 | O’Hare Doig, R.L., et al. 2017. Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma. BMC Neuroscience, 62. |
| 28130923 | 1:100 | Arancibia-Cárcamo, I.L., et al. 2017. Node of Ranvier length as a potential regulator of myelinated axon conduction speed. Elife, e23329. |
| 26888923 | not listed | Kim, K.X., et al. 2016. Maturation of NaV and KV channel topographies in the auditory nerve spike initiator before and after developmental onset of hearing function. . Journal of Neuroscience, 2111-2118. |
| 25948259 | 1:1000 | Hirono, M., et al. 2015. BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells.. Journal of Neuroscience, 7082-7094. |
| 25294986 | 1:500 | Tian, C., et al. 2014. Molecular identity of axonal sodium channels in human cortical pyramidal cells. . Frontiers in cellular neuroscience, 297. |
| 22675541 | not listed | Manning, C.F., et al. 2012. Benefits and pitfalls of secondary antibodies: why choosing the right secondary is of primary importance.. PLoS One, . |
| 21734302 | 1:250 | Lysakowski, A., et al. 2011. Molecular microdomains in a sensory terminal, the vestibular calyx ending.. Journal of Neuroscience, 10101-10114. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 31910261 | not listed | Lee, M., et al. 2020. Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain. Journal of Cell Biology, e201903033. |
| 30504823 | 1:1000 | Nelson, N.D., et al. 2020. Ankyrin-G Regulates Forebrain Connectivity and Network Synchronization via Interaction with GABARAP. Molecular Psychiatry, 2800-2817. |
| 31933626 | 1:500 | Alshammari, M.A., et al. 2019. Changes in the Fluorescence Tracking of NaV1.6 Protein Expression in a BTBR T+Itpr3tf/J Autistic Mouse Model. Neural Plasticity, 4893103. |
| 29857015 | 1:1000 | Huang, T., et al. 2019. In utero electroporation-based translating ribosome affinity purification identifies age-dependent mRNA expression in cortical pyramidal neurons. Neuroscience Research, 44-52. |
| 25948259 | not listed | Hirono, M., et al. 2015. BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells.. Journal of Neuroscience, 7082-7094. |
| 24259518 | 1:2000 | Dagley, L.F., et al. 2014. Quantitative proteomic profiling reveals novel region-specific markers in the adult mouse brain.. Proteomics, 241-261. |
| Additional Publications: Unspecified | ||
| PMID | Publication | |
| 28470148 | Kleinecke, S., et al. 2017. Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy. Elife, 6, p.e23332.. Elife, e23332. | |
| 27474220 | Doppler, K., et al. 2016. Auto-antibodies to contactin-associated protein 1 (Caspr) in two patients with painful inflammatory neuropathy. Brain, 2617-2630. | |
| 25732815 | D''Este, E., et al. 2015. STED nanoscopy reveals the ubiquity of subcortical cytoskeleton periodicity in living neurons.. Cell Report, 1246-1251. | |
| 25707359 | Chen, N., et al. 2015. Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes.. Biochimica et Biophysica Acta, 827-833. | |
| 25614025 | Hinman, J.D., et al. 2015. Molecular disorganization of axons adjacent to human lacunar infarcts.. Brain, 736-745. | |
| 25552556 | Jenkins, P.M., et al. 2015. Giant ankyrin-G: a critical innovation in vertebrate evolution of fast and integrated neuronal signaling.. PNAS: USA, 957-964. | |
| 25413837 | Miyazaki, H., et al. 2014. Singular localization of sodium channel β4 subunit in unmyelinated fibres and its role in the striatum.. Nature Communications, 5525. | |
| 25362470 | Trimarco, A., et al. 2014. Prostaglandin D2 synthase/GPR44: a signaling axis in PNS myelination.. Nature Neuroscience, 1682-1692. | |
| 25119334 | Salewski, R.P., et al. 2014. Transplantation of neural stem cells clonally derived from embryonic stem cells promotes recovery after murine spinal cord injury. Stem Cells and Development, 36-50. | |
| 25031414 | Bull, S.J., et al. 2014. Progressive disorganization of paranodal junctions and compact myelin due to loss of DCC expression by oligodendrocytes.. Journal of Neuroscience, 9768-9778. | |
| 24753086 | Yamada, J., et al. 2014. Age-related differences in oligodendrogenesis across the dorsal-ventral axis of the mouse hippocampus.. Hippocampus, 1017-1029. | |
| 24631588 | Leinders, M., et al. 2014. Differential distribution of PI3K isoforms in spinal cord and dorsal root ganglia: potential roles in acute inflammatory pain.. Pain, 1150-1160. | |
| 24599470 | Battefeld, A., et al. 2014. Heteromeric Kv7.2/7.3 channels differentially regulate action potential initiation and conduction in neocortical myelinated axons.. Journal of Neuroscience, 3719-3732. | |
| 24431446 | Yao, D., et al. 2014. Neuronal expression of GalNAc transferase is sufficient to prevent the age-related neurodegenerative phenotype of complex ganglioside-deficient mice.. Journal of Neuroscience, 880-891. | |
| 23842490 | Koehler, K.R., et al. 2013. Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture.. Nature, 217-221. | |
| 23565257 | Liu, R., et al. 2013. An efficient method for dorsal root ganglia neurons purification with a one-time anti-mitotic reagent treatment.. PLoS One, . | |
| 23447612 | Petrosyan, H.A., et al. 2013. Neutralization of inhibitory molecule NG2 improves synaptic transmission, retrograde transport, and locomotor function after spinal cord injury in adult rats.. Journal of Neuroscience, 4032-4043. | |
| 23426679 | Kondo, Y., et al. 2013. Spontaneous optic nerve compression in the osteopetrotic (op/op) mouse: a novel model of myelination failure.. Journal of Neuroscience, 3514-3525. | |
| 23365232 | Chen, C.D., et al. 2013. The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS.. Journal of Neuroscience, 1927-1939. | |
| 23291093 | Horn, K.E., et al. 2013. DCC expression by neurons regulates synaptic plasticity in the adult brain.. Cell Report, 173-185. | |
| 22886464 | Engelhardt, M., et al. 2013. Ankyrin-B structurally defines terminal microdomains of peripheral somatosensory axons.. Brian Structure and Function, 1005-1016. | |
| 23300814 | Takano, M., et al. 2012. MRI characterization of paranodal junction failure and related spinal cord changes in mice.. PLoS One, . | |
| 23109147 | Brambrink, A.M., et al. 2012. Isoflurane-induced apoptosis of oligodendrocytes in the neonatal primate brain.. Annals of Neurology, 525-535. | |
| 22911763 | Bin, J.M., et al. 2012. Oligodendrocyte precursor cell transplantation into organotypic cerebellar shiverer slices: a model to study myelination and myelin maintenance.. PLoS One, . | |
| 22623668 | Gasser, A., et al. 2012. An ankyrinG-binding motif is necessary and sufficient for targeting Nav1.6 sodium channels to axon initial segments and nodes of Ranvier.. Journal of Neuroscience, 7232-7243. | |
| 22449950 | Bangratz, M., et al. 2012. A mouse model of Schwartz-Jampel syndrome reveals myelinating Schwann cell dysfunction with persistent axonal depolarization in vitro and distal peripheral nerve hyperexcitability when perlecan is lacking.. The American Journal of Pathology, 2040-2055. | |
| 22348182 | Liazoghli, D., et al. 2012. Substrate Micropatterning as a New in Vitro Cell Culture System to Study Myelination.. ACS Chemical Neuroscience, 90-95. | |
| 22159130 | Reimer, M.M., et al. 2011. Rapid disruption of axon-glial integrity in response to mild cerebral hypoperfusion.. Journal of Neuroscience, 18185-18194. | |
| 21988176 | Sun, W., et al. 2011. Paranodal myelin damage after acute stretch in Guinea pig spinal cord.. Journal of Neurotrauma, 611-619. | |
| 21838927 | Roza, C., et al. 2011. Accumulation of Kv7.2 channels in putative ectopic transduction zones of mice nerve-end neuromas.. Molecular Pain, 58. | |
| 21390223 | Huff, T.B., et al. 2011. Real-time CARS imaging reveals a calpain-dependent pathway for paranodal myelin retraction during high-frequency stimulation.. PLoS One, . | |
| 21352229 | Shi, Y., et al. 2011. Acrolein induces myelin damage in mammalian spinal cord.. Journal of Neurochemistry, 554-564. | |
| 21248132 | Pohl, H.B., et al. 2011. Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage.. Journal of Neuroscience, 1069-1080. | |
| 21177993 | Hunanyan, A.S., et al. 2011. Alterations of action potentials and the localization of Nav1.6 sodium channels in spared axons after hemisection injury of the spinal cord in adult rats.. Journal of Neurophysiology, 1033-1044. | |
| 20980605 | Chang, K.J., et al. 2010. Oligodendrocyte myelin glycoprotein does not influence node of ranvier structure or assembly.. Journal of Neuroscience, 14476-14481. | |
| 20858739 | Crawford, D.K., et al. 2010. Oestrogen receptor beta ligand: a novel treatment to enhance endogenous functional remyelination.. Brain, 2999-3016. | |
| 20600647 | Luo, S., et al. 2010. Pulpitis increases the proportion of atypical nodes of Ranvier in human dental pulp axons without a change in Nav1.6 sodium channel expression.. Neuroscience, 1881-1887. | |
| 20534825 | Hunanyan, A.S., et al. 2010. Role of chondroitin sulfate proteoglycans in axonal conduction in Mammalian spinal cord.. Journal of Neuroscience, 7761-7769. | |
| 20392939 | Glasscock, E., et al. 2010. Kv1.1 potassium channel deficiency reveals brain-driven cardiac dysfunction as a candidate mechanism for sudden unexplained death in epilepsy.. Journal of Neuroscience, 5167-5175. | |
| 20102598 | Zoga, V., et al. 2010. KATP channel subunits in rat dorsal root ganglia: alterations by painful axotomy.. Molecular Pain, . | |
| 20053889 | Seidl, A.H., et al. 2010. Mechanisms for adjusting interaural time differences to achieve binaural coincidence detection.. Journal of Neuroscience, 70-80. | |
| 20007460 | Prolo, L.M., et al. 2009. The lysosomal sialic acid transporter sialin is required for normal CNS myelination.. Journal of Neuroscience, 15355-15265. | |
| 19805030 | Arnaud, E., et al. 2009. SH3TC2/KIAA1985 protein is required for proper myelination and the integrity of the node of Ranvier in the peripheral nervous system.. PNAS: USA, 17528-17533. | |
| 19800949 | Crawford, D.K., et al. 2009. Functional recovery of callosal axons following demyelination: a critical window.. Neuroscience, 1407-1421. | |
| 19535585 | Dours-Zimmermann, M.T., et al. 2009. Versican V2 assembles the extracellular matrix surrounding the nodes of ranvier in the CNS.. Journal of Neuroscience, 7731-7742. | |
| 19379822 | Dupree, J.L., et al. 2009. Myelin, DIGs, and membrane rafts in the central nervous system. Prostaglandins & Other Lipid Mediators, 118-129. | |
| 19270340 | Teigler, A., et al. 2009. Defects in myelination, paranode organization and Purkinje cell innervation in the ether lipid-deficient mouse cerebellum.. Human Molecular Genetics, 1897-1908. | |
| 19156860 | Ogawa, Y., et al. 2009. Proteomic analysis of optic nerve lipid rafts reveals new paranodal proteins.. Journal of Neuroscience Research, 3502-3510. | |
| 18945908 | Jarjour, A.A., et al. 2008. Maintenance of axo-oligodendroglial paranodal junctions requires DCC and netrin-1.. Journal of Neuroscience, 11003-11014. | |
| 18550753 | Martin, P.M., et al. 2008. Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component of nodes of Ranvier and axon initial segments. Journal of Neuroscience, 6111-6117. | |
| 18426592 | Luo, S., et al. 2008. Nav1.7 expression is increased in painful human dental pulp.. Molecular Pain, 16. | |
| 18400887 | Lasiene, J., et al. 2008. No evidence for chronic demyelination in spared axons after spinal cord injury in a mouse.. Journal of Neuroscience, 3887-3896. | |
| 16817858 | Rush, A.M., et al. 2006. Differential modulation of sodium channel Na(v)1.6 by two members of the fibroblast growth factor homologous factor 2 subfamily.. European Journal of Neuroscience, 2551-2562. | |
| 23995069 | Viganò, F., et al. 2013. Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain.. Nature Neuroscience, 1370-1372. | |