The Denver Post featured PhosphoSolutions in a front page article!
10 February 2017.
Authors: Kameron Simpson, Michael Browning
PhosphoSolutions addresses the reproducibility crisis by discussing some of the biggest contributing factors to the “antibody problem”, including steps that can be taken on both the production side as well as on the side of the end-user. We go in-depth to discuss the initial screening via Western Blot that should be done by researchers to confirm antibody quality. We then describe steps that should be taken by producers of polyclonal antibodies to ensure lot-to-lot consistency.
24 January 2011.
Authors: Amy J. Archuleta, Crystal A. Stutzke, Kristin M. Nixon, Michael D. Browning
PhosphoSolutions goes in-depth to discuss the essential protocols and methods necessary to create a phospho-specific antibody that works. We describe techniques used from the beginning to the end of the antibody development process. We start with antigen design and immunization, continue with antibody purification, and even discuss the best ways to characterize the phosphospecificity of the antibody in peptide ELISA and western blots.
15 September 2015. Author: Michael D. Browning
The scientific community is putting an increasing focus on antibody inconsistency. We believe that these issues can be overcome by addressing two of the biggest offenders: antibody validation and antibody variability. Antibody suppliers must address the variability problem so that scientists can provide validation.
We call this the Antibody Two-Step Solution.
Independent researchers writing for PLoS compared our FMRP phospho-antibody to another commercially available FMRP antibody. The results were clear: The PhosphoSolutions antibody had greater specificity and less variability.