Why do so many researchers prefer polyclonal antibodies?

In an article in Nature on antibody quality (Monya Baker, Nature  527:545-551, 2015) a study was cited in which antibodies were used in over 2000 studies.  Among these polyclonal antibodies were used in 1293 studies, monoclonals were used in 755 papers.  This preference for polyclonal antibodies has been echoed in a number of other more […]